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DETECTing Merkel Cell Polyomavirus in Merkel Tumors
Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer caused either by Merkel cell polyomavirus (MCV) T antigen expression, post-integration (~80% cases), or by UV-mediated DNA damage.
Reety Arora +4 more
doaj +3 more sources
Merkel Cell Polyomavirus Strains in Patients with Merkel Cell Carcinoma
We investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens, but none of the non ...
Antoine Touzé +10 more
doaj +4 more sources
Merkel Cell Polyomavirus in Cutaneous Swabs
To assess the usefulness of using cutaneous swabs to detect Merkel cell polyomavirus (MCPyV) DNA, we analyzed swabs from persons with Merkel cell carcinoma (MCC), others with skin diseases, and healthy volunteers.
Vincent Foulongne +6 more
doaj +3 more sources
From Merkel Cell Polyomavirus Infection to Merkel Cell Carcinoma Oncogenesis [PDF]
Merkel cell polyomavirus (MCPyV) infection causes near-ubiquitous, asymptomatic infection in the skin, but occasionally leads to an aggressive skin cancer called Merkel cell carcinoma (MCC).
Nathan A. Krump, Jianxin You
doaj +3 more sources
Merkel Cell Polyomavirus DNA in Persons without Merkel Cell Carcinoma [PDF]
Merkel cell polyomavirus (MCPyV) DNA was detected in 88% of Merkel cell carcinomas in contrast to 16% of other skin tumors. MCPyV was also found in anogenital and oral samples (31%) and eyebrow hairs (50%) of HIV-positive men and in forehead swabs (62 ...
Ulrike Wieland +4 more
doaj +3 more sources
Merkel Cell Polyomavirus in Respiratory Tract Secretions
Merkel cell polyomavirus (MCPyV), associated with Merkel cell carcinoma, was detected in 27 of 635 nasopharyngeal aspirate samples by real-time PCR. MCPyV was more commonly found in adults than in children.
Shan Goh +3 more
doaj +3 more sources
Merkel cell polyomavirus in Merkel cell carcinoma of Italian patients [PDF]
Background Merkel cell carcinoma (MCC) is a rare but very aggressive human malignancy of elderly or immunosuppressed patients. Clonal integration of a new human polyomavirus, the Merkel cell polyomavirus (MCPyV), has been reported in MCC patients.
Migliano Emilia +5 more
doaj +3 more sources
Merkel cell polyomavirus and Langerhans cell neoplasm [PDF]
Background The relationship between various external agents such as pollen, food, and infectious agents and human sensitivity exists and is variable depending upon individual’s health conditions. For example, we believe that the pathogenetic potential of
Ichiro Murakami +20 more
doaj +3 more sources
Merkel Cell Polyomavirus and Merkel Cell Carcinoma, France
To the Editor: Merkel cell carcinoma (MCC) is a primary cutaneous neuroendocrine tumor. This aggressive skin cancer is uncommon but increasing in frequency. During 1986–2001, incidence rate tripled; average annual increase was 8% (1). MCC shares epidemiologic features with Kaposi sarcoma, a malignant tumor associated with human herpesvirus 8 infection (
Vincent Foulongne +5 more
doaj +3 more sources
Merkel Cell Polyomavirus and Merkel Cell Carcinoma [PDF]
Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA human tumor viruses have been identified, with Merkel cell polyomavirus being the most recent one to be linked to cancer. This virus is associated with about 80% of Merkel cell carcinomas, a rare, but aggressive cutaneous malignancy.
Valeria Pietropaolo +2 more
openaire +6 more sources

