Results 41 to 50 of about 3,929 (170)
Transplant International, 2023 Long-term risk for malignancy is higher among solid organ transplant (SOT) recipients compared to the general population. Four non-hepatitis viruses have been recognized as oncogenic in SOT recipients—EBV, cause of EBV-associated lymphoproliferative ...
Alaa Atamna +4 more
doaj +1 more source
Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland
Emerging Infectious Diseases, 2014 We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion
Tingting Chen +13 more
doaj +1 more source
Prevalence of Merkel Cell Polyomavirus among Swiss Merkel Cell Carcinoma Patients [PDF]
Dermatology, 2010 <i>Background:</i> Merkel cell carcinoma (MCC) is a malignant neuroendocrine neoplasm which shares structural and immunohistochemical features with neuroectodermally derived cells. One hypothesis claims that it arises from Merkel cells, highly innervated neuroendocrine cells involved in mechanoreception in the skin.
Mangana, J +4 more
openaire +2 more sources
Neoadjuvant therapy in skin cancer: current evidence and future perspectives
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello +2 more
wiley +1 more source
RB1 inactivation in cutaneous carcinomas
Histopathology, Volume 88, Issue 4, Page 769-789, March 2026.Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv +8 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 2, Page 331-347, February 2026.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Dermatologica Sinica, 2010 Merkel cell carcinoma (MCC) is a rare malignancy with aggressive behavior mostly seen in the elderly and immunosuppressed patients. In 2008, the clonal integration of a new human polyomavirus, named Merkel cell polyomavirus (MCPyV), was found to be ...
Wen-Tsao Ho +4 more
doaj +1 more source
Current In Vitro and In Vivo Models to Study MCPyV-Associated MCC
Viruses, 2022 Merkel cell polyomavirus (MCPyV) is the only human polyomavirus currently known to cause human cancer. MCPyV is believed to be an etiological factor in at least 80% of cases of the rare but aggressive skin malignancy Merkel cell carcinoma (MCC). In these
Amanda S. W. Loke +2 more
doaj +1 more source
Merkel Cell Carcinoma: A Complete Response to Avelumab Immunotherapy
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Merkel cell carcinoma is an aggressive form of cancer with poor prognosis, particularly for individuals deemed unsuitable for surgical resection. With new immunotherapy agents being used alone or as an adjuvant treatment, improving long term outcomes are being seen, even for those deemed to be treated with palliative intent.
Eamonn Byrne +3 more
wiley +1 more source
International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source