Results 71 to 80 of about 3,929 (170)

Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency

Head &Neck, Volume 47, Issue 7, Page E82-E86, July 2025.
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi, James A. Stewart, Kirk Withrow, Carissa M. Thomas   +3 more
wiley   +1 more source

In Vivo Reprogramming Highlights Epigenetic Regulation That Shapes Cancer Hallmarks

Cancer Science, Volume 116, Issue 7, Page 1807-1814, July 2025.
In this review, the authors first introduce genetic aberrations that cause cancer development. Then, they illustrate the impact of epigenetic abnormalities in cancer, especially with reference to studies that use in vivo reprogramming technologies. Finally, the authors discuss the importance of histological evaluations of tumor tissue to understand non‐
Yosuke Yamada, Nao Sankoda, Yasuhiro Yamada   +2 more
wiley   +1 more source

The Sunrise of Tertiary Lymphoid Structures in Cancer

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT First considered as a negative epiphenomenon in autoimmune and inflammatory diseases, with possible deleterious consequences through the production of pathological autoantibodies and antiself T cells, tertiary lymphoid structures (TLS) have gained major scientific and clinical interest in cancer due to their association with better clinical ...
Juliette Rochefort, Gilles Marodon, Jean‐Luc Teillaud, Marie‐Caroline Dieu‐Nosjean   +3 more
wiley   +1 more source

A review of the epidemiology and treatment of Merkel cell carcinoma

Clinics, 2011
Merkel cell carcinoma is a very rare and aggressive neoplasm. Due to its rarity, therapeutic guidelines are not well established, especially for regionally advanced disease.
João Pedreira Duprat, Gilles Landman, João Victor Salvajoli, Eduard Rene Brechtbühl   +3 more
doaj   +1 more source

Detection of Merkel Cell Carcinoma Polyomavirus in Mucosal Merkel Cell Carcinoma

International Journal of Surgical Pathology, 2010
A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified.
Karen N, Wu, Peter A, McCue, Adam, Berger, Joseph R, Spiegel, Zi-Xuan, Wang, Agnieszka K, Witkiewicz   +5 more
openaire   +3 more sources

Rak neuroendokrynny skóry (Merkla) – aktualne poglądy na patogenezę oraz metody leczenia

Przegląd Dermatologiczny, 2011
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skincancer localized mostly on exposed, sun-damaged skin – on the headand neck. Although rapidly increasing incidence of MCC is observed,the pathogenesis of the tumour is unclear. Diagnosis
Beata Sosada, Ligia Brzezińska-Wcisło
doaj  

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient.

PLoS Pathogens, 2010
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden, René W A Janssens, Chris Lauber, Jan Nico Bouwes Bavinck, Alexander E Gorbalenya, Mariet C W Feltkamp   +5 more
doaj   +1 more source

Updates in the Management of Merkel Cell Carcinoma

Brazilian Journal of Oncology, 2019
Merkel cell carcinomas are rare cutaneous malignancies with neuroendocrine features that affect elderly individuals with a history of chronic sun exposure and immunosuppression.
Paulo Henrique do Amor Divino, Gabriel Passos Souza, Maurício Fernando Silva-Almeida Ribeiro, George Horta, Fabíola Ambrosio Silveira-Lima, Alessandra Corte Real-Salgues, Rodrigo Ramella Munhoz   +6 more
doaj   +1 more source

Unmasking hidden Merkel cell carcinoma recurrences: Three illustrative cases of patients with rising viral oncoprotein antibody levels and challenge of requiring multi-modal imaging to detect clinical disease

Radiology Case Reports
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a high risk of recurrence and metastasis. Regular surveillance through physical exams and imaging studies is crucial for the timely detection of recurrences.
Nora A. Alexander, BS, Paul Nghiem, MD, PhD, Delphine L. Chen, MD, Song Y. Park, MD   +3 more
doaj   +1 more source

Merkel Cell Polyomavirus and Cutaneous Merkel Cell Carcinoma [PDF]

Future Science OA, 2016
Minutilli, Ettore, Mulè, Antonino
openaire   +2 more sources