Results 201 to 210 of about 192,395 (356)

Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming

, 2021
She H, Hu Y, Y Zhou, Tan L, Yong‐Guan Zhu, Chao Ma, Yi‐Long Wu, W Chen, L Wang, Z Zhang, L Wang, Lei Liu, Li T   +12 more
openalex   +1 more source

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

Parathyroid Hormone Reprograms Osteoblast Metabolism [PDF]

Journal of Bone and Mineral Research, 2015
openaire   +2 more sources

Modulation of immune cells and metabolic reprogramming in efferocytosis. [PDF]

Cell Death Dis
Oliveira KC, Marcos CM, Penteado LA, Dejani NN, Moraes-Vieira PM, Medeiros AI.   +5 more
europepmc   +1 more source

Oxidative stress and reprogramming of mitochondrial function and dynamics as targets to modulate cancer cell behavior and chemoresistance [PDF]

, 2019
Domenicotti, C, Falone, S, Lisanti, MP
core   +3 more sources

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Endothelial Metabolic Reprogramming Links Diabetes to Atherosclerosis. [PDF]

Diabetes Metab Syndr Obes
Pan Y, Si J.
europepmc   +1 more source

GLP-1 receptor agonists synergistic effects of metabolic reprogramming and cardioprotection [PDF]

Xuan Wang, Mengmeng Qi, Lili Yang, Libo Yang, Xiaoyue Wang, Fang Zhang, Yukun Cui, Dongxin Wang, Yangang Wang, Wenshan Lv   +9 more
openalex   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Fueling asthma inflammation via bioenergetic metabolic reprogramming. [PDF]

Redox Biol
Mulya A, Janocha AJ, Novotny MV, Reichard A, Hamm E, Chen R, Mey JT, Peterson L, Mavrakis L, Beck B, Koo M, Sharp J, Pennington E, McCarroll S, Micklewright S, Zhang P, Koziol-White C, Aronica M, Comhair SAA, Kirwan JP, Barnard J, Panettieri RA, Darley-Usmar V, Erzurum SC.   +23 more
europepmc   +1 more source