Results 211 to 220 of about 192,395 (356)

TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy [PDF]

, 2018
Lan Huang, Huaxi Xu, Guangyong Peng
openalex   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu, Mengqin Yuan, Yini Shang, Jiahao Chen, Fei Hou, Lihong Wang, Wei Jiang   +6 more
wiley   +1 more source

Advances in Metabolic Reprogramming and Immune Regulatory Mechanisms in Lung Cancer. [PDF]

Oncol Res
Li X, Li X, Wu H, Li R.
europepmc   +1 more source

Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma

, 2022
Rui Sun, Chao Lei, Liang Chen, Liqing He, Haixun Guo, Xiang Zhang, Wenke Feng, Jun Yan, Craig J. McClain, Zhongbin Deng   +9 more
openalex   +2 more sources

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

The role of glucose metabolic reprogramming in myocarditis and advances in therapeutic strategies. [PDF]

Front Cardiovasc Med
Liu X, Han B.
europepmc   +1 more source

Metabolic Reprogramming of Endothelial-Related Pathways in COVID-19 Patients Treated with Hyperbaric Oxygen Therapy: A Randomized Clinical Trial [PDF]

Natalia Jermakow, Klaudia Brodaczewska, Kot Jacek, Krzysztof Urbanowicz, Jacek Turyn, Ryszard T. Smoleński, Arkadiusz Lubas, Krzysztof Kłos, Jacek Siewiera   +8 more
openalex   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

The controversial role of metabolic reprogramming in anti-tumor therapy resistance. [PDF]

Discov Oncol
Xu Y, Wang Y, Fu Q, Yao Y, Zhou Y.
europepmc   +1 more source

Metabolic reprogramming during hepatitis B disease progression offers novel diagnostic and therapeutic opportunities [PDF]

, 2017
Jesse J. R. Masson, Hugh Billings, Clovis S. Palmer   +2 more
openalex   +1 more source