Results 41 to 50 of about 184,184 (276)

Transcriptomics and metabolomics reveal the molecular and metabolic adaptation to heat stress in Manila clam Ruditapes philippinarum

Frontiers in Marine Science, 2023
Temperature is an important environmental factor affecting metabolism, growth and life activities of marine bivalves. To reveal the molecular and metabolic responses to heat stress, comparative transcriptomics and metabolomics were performed in the ...
Hao Jing, Hao Jing, Hao Jing, Liqing Zhou, Liqing Zhou, Yiqiang Gao, Yiqiang Gao, Yiqiang Gao, Zhihong Liu, Zhihong Liu, Biao Wu, Biao Wu, Xiujun Sun, Xiujun Sun, Kang Tu   +14 more
doaj   +1 more source

Updates in metabolomics tools and resources: 2014-2015 [PDF]

, 2016
Data processing and interpretation represent the most challenging and time-consuming steps in high-throughput metabolomic experiments, regardless of the analytical platforms (MS or NMR spectroscopy based) used for data acquisition.
Misra, Biswapriya B., van der Hooft, Justin   +1 more
core   +1 more source

Metabolomics-based treatment for chronic diseases: results from a multidisciplinary clinical study

BMJ Nutrition, Prevention & Health
Background Non-communicable diseases (NCDs), known as chronic diseases, significantly impact patients’ quality of life (QoL) and increase medical expenses.
Aristidis Tsatsakis, Dimitris Tsoukalas, Evangelia Sarandi, Vassilleios Fragoulakis, Symeon Xenidis, Maria Mhliopoulou, Maria Charta, Efstathia Paramera, Evangelos Papakonstantinou   +8 more
doaj   +1 more source

Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]

, 2010
Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
A Kamleh, A Scalbert, AK Chavali, Andris Jankevics, BO Keller, C Bern, C Christin, CC HsuChen, D Kumar, David G. Watson, DS Wishart, E Cauchetier, E Fahy, F Chappuis, F Hong, FR Opperdoes, G Barratt, Graham H. Coombs, H Ogata, HC Maltezou, HJ Atherton, HP de Koning, HW Murray, J Alvar, J Trygg, J Vandesompele, JC Mottram, Jean-Claude Dujardin, JV Olsen, K Zhang, K Zhang, Kirstyn Brunker, KW Tintaya, M Basselin, M Basselin, M Rakotomanga, MA Basinger, MA Doyle, MA Kamleh, MA Kamleh, MB Eisen, MK Wassef, MZ Alam, N Mbongo, N Van Meirvenne, R Breitling, R Breitling, R Breitling, RA Scheltema, RA Scheltema, RA Scheltema, Rainer Breitling, Richard A. Scheltema, Ruben t'Kindt, S Rijal, S Sundar, Saskia Decuypere, Suman Rijal, T Laurent, T Naderer, Timothy G. Geary, VP Shah, W Windig, WB Dunn   +63 more
core   +6 more sources

Application of clinical blood metabogram for diagnosis of early-stage Parkinson’s disease: a pilot study

Frontiers in Molecular Biosciences
In terms of time, cost, and reproducibility of clinical laboratory tests, a mass spectrometric clinical blood metabogram (CBM) enables the investigation of the blood metabolome.
Petr G. Lokhov, Oxana P. Trifonova, Elena E. Balashova, Dmitry L. Maslov, Michael V. Ugrumov, Alexander I. Archakov   +5 more
doaj   +1 more source

Targeted Metabolomic Analysis of Serum Fatty Acids for the Prediction of Autoimmune Diseases

Frontiers in Molecular Biosciences, 2019
Autoimmune diseases (ADs) are rapidly increasing worldwide and accumulating data support a key role of disrupted metabolism in ADs. This study aimed to identify an improved combination of Total Fatty Acids (TFAs) biomarkers as a predictive factor for the
Dimitris Tsoukalas, Dimitris Tsoukalas, Dimitris Tsoukalas, Vassileios Fragoulakis, Evangelia Sarandi, Evangelia Sarandi, Anca Oana Docea, Evangelos Papakonstaninou, Gerasimos Tsilimidos, Chrysanthi Anamaterou, Persefoni Fragkiadaki, Michael Aschner, Aristidis Tsatsakis, Aristidis Tsatsakis, Nikolaos Drakoulis, Daniela Calina   +15 more
doaj   +1 more source

Effects of Different Monochromatic Light Combinations on Cecal Microbiota Composition and Cecal Tonsil T Lymphocyte Proliferation

Frontiers in Immunology, 2022
Emerging data demonstrated that the gut microbiota plays an important role in protecting the integrity of the epithelial barrier, forming a mucosal immune system, and maintaining intestinal homeostasis through its metabolites.
Yijia Zhang, Zixu Wang, Yulan Dong, Jing Cao, Yaoxing Chen   +4 more
doaj   +1 more source

Extraction for Metabolomics: Access to The Metabolome

Phytochemical Analysis, 2014
ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y., Choi, Y.H., Verpoorte, R., Wilson, E.G.   +3 more
openaire   +3 more sources

A novel method for interrogating receiver operating characteristic curves for assessing prognostic tests

Diagnostic and Prognostic Research, 2017
Background Disease prevalence is rarely explicitly considered in the early stages of the development of novel prognostic tests. Rather, researchers use the area under the receiver operating characteristic (AUROC) as the key metric to gauge and report ...
Grégoire Thomas, Louise C. Kenny, Philip N. Baker, Robin Tuytten   +3 more
doaj   +1 more source

Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]

, 2019
Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica, ECRIS integrated in the Spanish AIDS Research Network, Herrero, Pol, Jimenez-Leon, María Reyes, Leal, Manuel, Peraire, Joaquim, Portilla, Irene, Rodríguez-Gallego, Esther, Ruiz-Mateos, Ezequiel, Rull, Anna, Tarancon-Diez, Laura, Vidal, Francesc, Viladés, Consuelo   +12 more
core   +2 more sources