Results 111 to 120 of about 11,908 (171)

Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells

, 2012
Mitochondrial dynamics and distribution is critical for their role in bioenergetics and cell survival. We investigated the consequence of altered fission/fusion on mitochondrial function and motility in INS-1E rat clonal β-cells.
Wiederkehr, Andreas, Park, Kyu-Sang, Wollheim, Claes   +2 more
core   +1 more source

Eucalyptus camaldulensis leaf extract enhances thalidomide efficacy in acute myeloid leukemia cells through modulation of mitochondrial energetics. [PDF]

BMC Complement Med Ther
Ismail SE, Hassan AA, Elkhedel AA, Fakhry AM, Khalifa EA, Toto SM.   +5 more
europepmc   +1 more source

Procyanidins A1 and B1 Suppress PEDV CV777 by Modulating Mitophagy. [PDF]

Viruses
Weng Y, Li J, Ma C, Wang J, Wang X.
europepmc   +1 more source

Fertility effect of the knockout of Mitofusin 1 on murine oocytes

, 2018
Fertility is directly related to oocyte developmental competence. In this context, oocyte mitochondria play a crucial role and have become an important target in assisted reproduction therapies.
Carvalho, Karen Freire
core  

A Metal-Phenolic Nanocluster Orchestrates Mito-Ca²⁺ Metabolic Autonomy for Tumor Ca²⁺ Interference Therapy. [PDF]

Adv Sci (Weinh)
Chen R, Huang J, Wang Y, Yao S, Wu F, Liu J, Song C, Lin L, Lin X, Deng Y, Zhang C, Huang Z, Huang Z, Xie L.   +13 more
europepmc   +1 more source

The effect of COQ10 on mRNA expression of Mfn1 and Mfn2 genes in the liver of lead-infected rats

Background and Objective: Lead poisoning has harmful effects on various body organs. Coenzyme Q10 (COQ10) plays a decisive role in many biological activities, such as intracellular antioxidant protection. Apoptosis is expressed and regulated in the liver
Khodarahmi , Parvin, Salehipour , Masoud, Sabzizadeh , Pegah   +2 more
core  

A combined artificial intelligence-wet lab approach identifies a pivotal role of the NAD⁺-mitophagy axis on aging and neurodegeneration. [PDF]

Alzheimers Dement
Lautrup S, Cao SQ, Long X, Liu BHM, Escobar-Doncel B, Ferrante A, Frank J, Schmauck-Medina T, Leung GHD, Liang KX, Lu N, Veverova K, Vyhnalek M, Pun FW, Zhavoronkov A, Fang EF.   +15 more
europepmc   +1 more source

EPS8 Differentially Regulates Antioxidant Defense and Mitochondrial Homeostatic Signaling in LNCaP and Enzalutamide-resistant LNCaP Cells. [PDF]

Cancer Genomics Proteomics
Chen SH, Wu CH, Hsieh PF, Huang WC, Yang YL, Lin VC, Lin MW.   +6 more
europepmc   +1 more source

Mitochondrial Dynamics in Cancer Progression and Therapy Resistance: Emerging Roles in Metabolic Reprogramming, Biomarker Discovery, and Precision Medicine. [PDF]

Cells
Penugurti V, Kant R, Hsu CC.
europepmc   +1 more source

MTFR2 regulated the proliferation, apoptosis, migration, and invasion of endometrial cancer cells through the Drp1/MFN1 signaling pathway mediated mitochondrial fission. [PDF]

Transl Cancer Res
Bai X, Wei M, Wang Q, Yang Y.
europepmc   +1 more source