Genetic disruption of mitochondrial dynamics and stasis leads to liver injury and tumorigenesis. [PDF]
Ma X +14 more
europepmc +1 more source
Mitochondrial development and remodeling occur at pancreatic progenitor stage during induction of stem cell-derived islet organoids. [PDF]
Diane A +4 more
europepmc +1 more source
DMOG pretreatment restores osteogenic-adipogenic balance and mitochondrial function in ONFH BMSCs through the HIF-1α/Homer3 pathway. [PDF]
Chen Q +6 more
europepmc +1 more source
Elovl6 inhibits colorectal cancer progression through stearic acid-mediated mitochondrial fusion and metabolic reprogramming. [PDF]
Bi Z +8 more
europepmc +1 more source
Extracellular vesicle delivery of Myricetin suppresses ovarian cancer through mitochondrial dynamics by downregulating the ECM1/NF-κB/TGFβ signaling pathway. [PDF]
Pande K, Singh SA, Kannan A.
europepmc +1 more source
Effect of (-)-Epicatechin on Mitochondrial Homeostasis in Skeletal Muscle of Female Obese Rats. [PDF]
Herrera-Cogco EC +6 more
europepmc +1 more source
Hint2 deficiency aggravates mitochondria-associated ferroptosis in lung ischemia-reperfusion injury. [PDF]
Liu Y +8 more
europepmc +1 more source
MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice [PDF]
MFN1 (Mitofusin 1) and MFN2 (Mitofusin 2) are GTPases essential for mitochondrial fusion. Published studies revealed crucial roles of both Mitofusins during embryonic development. Despite the unique mitochondrial organization in sperm flagella, the biological requirement in sperm development and functions remain undefined.
Pengxiang Wang, Yuan Wang
exaly +4 more sources
Mitochondria elongation is mediated through SIRT1-mediated MFN1 stabilization
Mitochondria are highly dynamic organelles that change size and morphology by fusing together or dividing through fission. In response to cellular cues, signaling cascades may post-translationally modify mitochondria-shaping proteins, which lead to a change in mitochondria morphology.
Nguyen Thi Kim Oanh +2 more
exaly +4 more sources

