Results 21 to 30 of about 1,371 (176)

Establishment of a practical methodology for evaluating equieffective dose of individual patients based on RT-PHITS [PDF]

EJNMMI Physics
Background The RadioTherapy package based on PHITS (RT-PHITS) is an individual dosimetry system applicable to both targeted radionuclide therapy (TRT) and external radiotherapy.
Tatsuhiko Sato, Takuya Furuta, Hidetaka Sasaki, Tadashi Watabe   +3 more
doaj   +2 more sources

A systematic analysis of the particle irradiation data ensemble in the key of the microdosimetric kinetic model: Should clonogenic data be used for clinical relative biological effectiveness? [PDF]

Radiother Oncol, 2023
Suárez-García D, Cortés-Giraldo MA, Bertolet A.   +2 more
europepmc   +2 more sources

Relation between Lineal Energy Distribution and Relative Biological Effectiveness for Photon Beams according to the Microdosimetric Kinetic Model [PDF]

Journal of Radiation Research, 2011
Our cell survival data showed the obvious dependence of RBE on photon energy: The RBE value for 200 kV X-rays was approximately 10% greater than those for mega-voltage photon beams. In radiation therapy using mega-voltage photon beams, the photon energy distribution outside the field is different with that in the radiation field because of a large ...
H. Okamoto, T. Kanai, Y. Kase, Y. Matsumoto, Y. Furusawa, Y. Fujita, H. Saitoh, J. Itami, T. Kohno   +8 more
openaire   +4 more sources

Mixed- and multi-relative biological effectiveness model simultaneous optimization in carbon ion radiotherapy: A proof-of-concept [PDF]

Physics and Imaging in Radiation Oncology
Background and purpose: In carbon ion radiotherapy (CIRT), different relative biological effectiveness (RBE) models have been used for calculating RBE-weighted dose (DRBE).
Aaron Paul Osburg, Peter Lysakovski, Giuseppe Magro, Semi Harrabi, Thomas Haberer, Amir Abdollahi, Jürgen Debus, Thomas Tessonnier, Andrea Mairani   +8 more
doaj   +2 more sources

pyMKM: An Open-Source Python Package for Microdosimetric Kinetic Model Calculation in Research and Clinical Applications

Computation
Among existing radiobiological models, the MKM and its extensions (SMK and OSMK) have demonstrated strong predictive capabilities but remain computationally demanding.
Giuseppe Magro, Vittoria Pavanello, Yihan Jia, Loïc Grevillot, Lars Glimelius, Andrea Mairani   +5 more
doaj   +2 more sources

The Mayo Clinic Florida Microdosimetric Kinetic Model of Clonogenic Survival: Application to Various Repair-Competent Rodent and Human Cell Lines. [PDF]

Int J Mol Sci, 2022
Parisi A, Beltran CJ, Furutani KM.
europepmc   +2 more sources

Carbon Ion Dose Constraints in the Head and Neck and Skull Base: Review of MedAustron Institutional Protocols [PDF]

International Journal of Particle Therapy, 2021
Background: Dose constraints are of paramount importance for the outcome of any radiotherapy treatment. In this article, we report dose-volume constraints as well as currently used fractionation schedules for carbon ion radiotherapy as applied in ...
Piero Fossati, MD, Ana Perpar, MD, Markus Stock, PhD, Petra Georg, MD, Antonio Carlino, PhD, Joanna Gora, PhD, Giovanna Martino, MSc, Eugen B. Hug, MD   +7 more
doaj   +1 more source

First theoretical determination of relative biological effectiveness of very high energy electrons

Scientific Reports, 2021
Very high energy electrons (VHEEs, E > 70 MeV) present promising clinical advantages over conventional beams due to their increased range, improved penumbra and relative insensitivity to tissue heterogeneities.
Rachel Delorme, Thongchai A. M. Masilela, Camille Etoh, François Smekens, Yolanda Prezado   +4 more
doaj   +1 more source

A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy

Cells, 2020
Boron neutron capture therapy (BNCT) is a type of radiation therapy for eradicating tumor cells through a 10B(n,α)7Li reaction in the presence of 10B in cancer cells.
Yusuke Matsuya, Hisanori Fukunaga, Motoko Omura, Hiroyuki Date   +3 more
doaj   +1 more source

Across the stages: a multiscale extension of the generalized stochastic microdosimetric model (MS-GSM2) to include the ultra-high dose rate

Frontiers in Physics, 2023
Ultra-high dose rate (UHDR) irradiations with different types of radiation have shown a larger sparing of normal tissue and unchanged tumor control with respect to conventional delivery.
Marco Battestini, Marco Battestini, Marta Missiaggia, Andrea Attili, Francesco Tommasino, Francesco Tommasino, Chiara La Tessa, Francesco G. Cordoni, Francesco G. Cordoni, Emanuele Scifoni   +9 more
doaj   +1 more source