Results 91 to 100 of about 4,115 (133)

miR-590-5P inhibits the progression of tongue squamous cell carcinoma by targeting FasL.

International journal of clinical and experimental pathology
This study evaluated microRNA-590-5P (miR-590-5P), which functions as an anti-onco-miRNA in TSCC by downregulating FasL expression.In this study, immunohistochemistry was used to detect FasL protein expression in 30 OSCC samples and 8 normal oral mucosa tissue samples. Target Scan was used to predict miRNAs that target FasL.
Yanxue, Xu, Tongtong, Han, Youming, Zhu, Qiaoer, Chen   +3 more
openaire   +1 more source

The Practical Landscape of Cytokine‐Targeted miRNAs to Enhance NK Cell Function in Cancer Immunotherapy: A Bioinformatic Analysis

Cancer Reports
Introduction Suppression within the tumor microenvironment (TME) hampered natural killer (NK) cells and their role in cancer immunotherapy. This study explores how interleukin (IL) signaling (IL‐12A, IL‐12B, IL‐15, IL‐18) and interferon gamma (IFNG or ...
Arefeh Zabeti Touchaei, Sogand Vahidi, Ali Akbar Samadani   +2 more
doaj   +1 more source

miR-590-5p promotes liver cancer growth and chemotherapy resistance through directly targeting FOXO1.

American journal of translational research
miR-590-5p functions as an onco-miR or an anti-onco-miR in various types of cancers. However, the exact role of miR-590-5p in liver cancer remains to be elucidated. In the present study, we explored the predictive role of miR-590-5p expression in liver cancer patients.
Guiqing, Jia, Youyin, Tang, Gang, Deng, Dan, Fang, Jie, Xie, Lvnan, Yan, Zheyu, Chen   +6 more
openaire   +1 more source

Inhibition of LOXL1-AS1 alleviates oxidative low-density lipoprotein induced angiogenesis via downregulation of miR-590-5p mediated KLF6/VEGF signaling pathway. [PDF]

Cell Cycle, 2021
Cheng X, Liu Z, Zhang H, Lian Y.
europepmc   +1 more source

miR-590-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting FGF18 in osteoarthritis.

American journal of translational research
To investigate the potential miRNA targeting FGF18, and its role in regulating the proliferation, apoptosis and inflammation in human primary chondrocytes.The normal human chondrocytes were induced by IL-1β to mimic OA in vitro. qPCR and Western blotting were performed to evaluate the expression of FGF18.
Peng, Jiang, Xixi, Dou, Shuaiguang, Li, Qingwen, Jia, Peixue, Ling, Hongyu, Liu, Qiuju, Han, Shui, Sun   +7 more
openaire   +1 more source

Circular RNA hsa_circ_0005114-miR-142-3p/miR-590-5p-adenomatous polyposis coli protein axis as a potential target for treatment of glioma. [PDF]

Oncol Lett, 2021
Wei B, Wang L, Zhao J.
europepmc   +1 more source

[Retracted] Knockdown of lncRNA NUTM2A-AS1 inhibits lung adenocarcinoma cell viability by regulating the miR-590-5p/METTL3 axis. [PDF]

Oncol Lett
Wang J, Zha J, Wang X.
europepmc   +1 more source

The Frog Skin-Derived Antimicrobial Peptide Suppresses Atherosclerosis by Modulating the KLF12/p300 Axis Through miR-590-5p. [PDF]

Int J Mol Sci
Fan F, Li MM, Qiu ZP, Li ZJ, Shang DJ.
europepmc   +1 more source

Retraction Note: Circular RNA circDCUN1D4 suppresses hepatocellular carcinoma development via targeting the miR-590-5p/ TIMP3 axis. [PDF]

Mol Cancer
Li H, Su B, Jiang Y, Zhang B, Du R, Song C, Hou B, Xu K, Wu L, Gu Y.   +9 more
europepmc   +1 more source

Circ-GTF2I/miR-590-5p Axis Aggravates Myocardial Ischemia-Reperfusion Injury by Regulating Kelch Repeat and BTB Domain-Containing Protein 7.

Evid Based Complement Alternat Med, 2022
Yuan C, Lu J, Chen Z, Zhou Q.
europepmc   +1 more source