Results 1 to 10 of about 447,640 (362)
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology
Nucleic Acids Research, 2020 miRNet is an easy-to-use, web-based platform designed to help elucidate microRNA (miRNA) functions by integrating users' data with existing knowledge via network-based visual analytics. Since its first release in 2016, miRNet has been accessed by >20 000
Le Chang, Jianguo Xia
exaly +2 more sources
Ultrasensitive detection of miRNA with an antimonene-based surface plasmon resonance sensor
Nature Communications, 2019 MicroRNA exhibits differential expression levels in cancer and can affect cellular transformation, carcinogenesis and metastasis. Although fluorescence techniques using dye molecule labels have been studied, label-free molecular-level quantification of ...
Tianyu Xue, weiyuan Liang, Yuanhui Sun
exaly +2 more sources
Scientific Reports, 2018 Multiple studies suggested using different miRNAs as biomarkers for prognosis of hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database from independent datasets to enable an independent validation of previously published ...
Ádám Nagy +2 more
exaly +2 more sources
A Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling
Science, 2006 Mark Estelle +2 more
exaly +2 more sources
The expression profile of exosomal miRNAs in cervical cancer cells (HeLa) compared to normal cells and evaluating the key genes related to them [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023 Introduction: Cervical cancer is the fourth most common cancer among women worldwide and is a heterogeneous disease. The exosomal miRNAs could be applied as diagnostic biomarkers and therapeutic targets in cervical cancer. The present study was performed
Marzieh Naderi Boldaji +2 more
doaj +1 more source
miRNA: A Promising Therapeutic Target in Cancer
International Journal of Molecular Sciences, 2022 microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by complementarity pairing. Since discovery, they have been reported to be involved in a variety of biological functions and pathologies including cancer.
Amrutha Menon +4 more
semanticscholar +1 more source
miRNA interplay: mechanisms and consequences in cancer
Disease Models & Mechanisms, 2021 Canonically, microRNAs (miRNAs) control mRNA expression. However, studies have shown that miRNAs are also capable of targeting non-coding RNAs, including long non-coding RNAs and miRNAs.
Meredith Hill, Nham T Tran
semanticscholar +1 more source
The miRNA–target interactions: An underestimated intricacy
Nucleic Acids Research, 2023 MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their cellular regulatory impact is determined not solely by their sheer number, which likely amounts to >2000 individual miRNAs in human, than by the regulatory ...
C. Diener, Andreas Keller, E. Meese
semanticscholar +1 more source
High-throughput sequencing analysis of mirna expression in embryonic chicken breast muscle [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 The embryonic period is a critical period for the development of muscle and adipose tissue in chickens. MicroRNAs (miRNAs) have been shown to play important roles in various biological processes, but little is known about miRNAs in chicken embryos.
Lei ZHANG +3 more
doaj +1 more source
A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice
iScience, 2020 Summary: The development of adequate model systems to study human malignancies is crucial for basic and preclinical research. Here, we exploit the “immune-privileged” developmental time window to achieve orthotopic xenotransplantation of human brain ...
Nadin Hoffmann +5 more
doaj +1 more source