Results 1 to 10 of about 432,940 (247)
Diagnostic and Prognostic Circulating MicroRNA in Acute Stroke: A Systematic and Bioinformatic Analysis of Current Evidence [PDF]
Journal of Stroke, 2021 Background and Purpose Stroke is the second leading cause of death and disability worldwide and its diagnosis, and assessment of prognosis, remains challenging. There is a need for improved diagnostic and prognostic biomarkers.
Jorin Bejleri +4 more
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The expression profile of exosomal miRNAs in cervical cancer cells (HeLa) compared to normal cells and evaluating the key genes related to them [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023 Introduction: Cervical cancer is the fourth most common cancer among women worldwide and is a heterogeneous disease. The exosomal miRNAs could be applied as diagnostic biomarkers and therapeutic targets in cervical cancer. The present study was performed
Marzieh Naderi Boldaji +2 more
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Scientific Reports, 2023 In mammals, the suprachiasmatic nucleus of the hypothalamus is the master circadian pacemaker that synchronizes the clocks in the central nervous system and periphery, thus orchestrating rhythms throughout the body.
Lidia Giantomasi +6 more
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A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice
iScience, 2020 Summary: The development of adequate model systems to study human malignancies is crucial for basic and preclinical research. Here, we exploit the “immune-privileged” developmental time window to achieve orthotopic xenotransplantation of human brain ...
Nadin Hoffmann +5 more
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The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies
Translational Research in Urology, 2022 Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade.
Helia Azodian Ghajar +1 more
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Glial Bmal1 role in mammalian retina daily changes
Scientific Reports, 2022 Visual information processing in the retina requires the rhythmic expression of clock genes. The intrinsic retinal circadian clock is independent of the master clock located in the hypothalamic suprachiasmatic nucleus and emerges from retinal cells ...
Serena Riccitelli +8 more
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Zdorovʹe Rebenka, 2022 The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
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High-throughput sequencing analysis of mirna expression in embryonic chicken breast muscle [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 The embryonic period is a critical period for the development of muscle and adipose tissue in chickens. MicroRNAs (miRNAs) have been shown to play important roles in various biological processes, but little is known about miRNAs in chicken embryos.
Lei ZHANG +3 more
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Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
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miR-34 – A microRNA Replacement Therapy Is Headed to the Clinic
Frontiers in Genetics, 2012 MicroRNA-34 is a master regulator of tumor suppression. It is downregulated in numerous cancers and inhibits malignant growth by repressing genes involved in various oncogenic signaling pathways.
Andreas G Bader
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