Results 21 to 30 of about 21,203 (224)
, 2022 (A-A’) Violin plot of TFAP2-activated MITF peaks at TFAP2-pioneered-and-inhibited enhancers, which are potentially TFAP2/MITF co-inhibited enhancers, showing (A) anti-MITF CUT&RUN and (A’) ATAC-Seq profiles in TFAP2-KO and WT cells.
Hannah E. Seberg (3804376) +8 more
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TFAP2 paralogs modulate the binding of MITF.
, 2022 (A) Density heatmap centered on 9,413 peaks co-bound by TFAP2A and MITF, showing anti-TFAP2, anti-MITF, ATAC-seq, and anti-H3K27Ac CUT&RUN profiles in SK-MEL-28 cells. Regions shown are +/- 5 kb from peak center. (B) Violin plot showing anti-MITF CUT&RUN
Hannah E. Seberg (3804376) +8 more
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Density heatmap of TFAP2 regulated MITF peaks.
, 2022 Density heatmap centered on TFAP2-activated MITF peaks (first cluster), mutually dependent (mutually activated) peaks (second cluster), TFAP2-inhibited MITF peaks and (third cluster) and TFAP2-independent MITF peaks (forth cluster), showing two ...
Hannah E. Seberg (3804376) +8 more
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Pro-Survival Role of MITF in Melanoma [PDF]
Journal of Investigative Dermatology, 2015 Melanoma is a therapy-resistant skin cancer due to numerous mechanisms supporting cell survival. Although components of melanoma cytoprotective mechanisms are overexpressed in many types of tumors, some of their regulators are characteristic for melanoma.
Hartman, Mariusz L., Czyz, Malgorzata
openaire +2 more sources
Pleurochrysis carterae Hot-Water Extract Inhibits Melanogenesis in Murine Melanoma Cells
Cosmetics, 2019 In this study, we examined the effect of a hot-water extract of coccolithophore Pleurochrysis carterae on melanogenesis in B16F1 and B16F10 melanoma cells. P.
Kazuomi Sato +3 more
doaj +1 more source
Characterizing the Coding Region Determinant-Binding Protein (CRD-BP)-Microphthalmia-associated Transcription Factor (MITF) mRNA interaction. [PDF]
PLoS ONE, 2017 Coding region determinant-binding protein (CRD-BP) binds to the 3'-UTR of microphthalmia-associated transcription factor (MITF) mRNA to prevent its targeted degradation by miR-340.
Gerrit van Rensburg +2 more
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MRGPRX2 signaling involves the Lysyl-tRNA synthetase and MITF pathway
Frontiers in Immunology, 2023 MRGPRX2, a G-protein-coupled-seven transmembrane domain receptor, is mainly expressed in mast cells and neurons and is involved in skin immunity and pain. It is implicated in the pathophysiology of non-IgE-mediated immediate hypersensitivity and has been
Yanru Guo +14 more
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International Journal of Circumpolar Health, 2019 Waardenburg syndrome (WS) is an orphan genetic disease with autosomal dominant pattern of inheritance characterised by varying degrees of hearing loss accompanied by skin, hair and iris pigmentation abnormalities. Four types of WS differing in phenotypic
Nikolay A. Barashkov +12 more
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Asian Pacific Journal of Tropical Medicine, 2019 Objective: To determine the effect of extracts from Phyllanthus acidus (P. acidus) (L.) Skeels and Rhinacanthus nasutus (R. nasutus) (L.) Kurz leaves on melanogenesis and the underlying mechanism in normal human epidermal melanocytes (NHEM) and a ...
Moragot Chatatikun +4 more
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Mitf regulates osteoclastogenesis by modulating NFATc1 activity [PDF]
, 2014 Transcription factors Mitf and NFATc1 share many downstream targets that are critical for osteoclastogenesis. Since RANKL signals induce/activate both NFATc1 and Mitf isoform-E (Mitf-E), a tissue-restricted Mitf isoform in osteoclasts, it is plausible ...
Li, Mengtao, Lu, Ssu-Yi, Lin, Yi-Ling
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