Results 1 to 10 of about 337,666 (144)

Players in Mitochondrial Dynamics and Female Reproduction

Frontiers in Molecular Biosciences, 2021
Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and mitochondrial quality control.
Weiwei Zou, Weiwei Zou, Weiwei Zou, Dongmei Ji, Dongmei Ji, Dongmei Ji, Zhiguo Zhang, Zhiguo Zhang, Zhiguo Zhang, Li Yang, Yunxia Cao, Yunxia Cao, Yunxia Cao   +12 more
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Correcting abnormal mitochondrial dynamics to facilitate tumor treatment

Mitochondrial Communications, 2023
Mitochondrial dynamics are closely related to various cellular physiological activities, including cell proliferation, homeostasis, and cell migration, and are regulated by a variety of enzymes, proteins and cytokines.
Bowen Yang, Yumeng Lin, Ying-Qiang Shen
doaj   +1 more source

A neuronal network of mitochondrial dynamics regulates metastasis. [PDF]

, 2016
The role of mitochondria in cancer is controversial. Using a genome-wide shRNA screen, we now show that tumours reprogram a network of mitochondrial dynamics operative in neurons, including syntaphilin (SNPH), kinesin KIF5B and GTPase Miro1/2 to localize
Aguinaldo, Angeline, Altieri, Dario C., Bosari, Silvano, Bryant, Kelly G., Caino, M. Cecilia, Cohen, Andrew R., Ferrero, Stefano, Gabrilovich, Dmitry I., Hayden, James E., Kossenkov, Andrew V., Languino, Lucia R., Morotti, Annamaria, Seo, Jae Ho, Vaira, Valentina, Wait, Eric   +14 more
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In silico simulation of reversible and irreversible swelling of mitochondria: The role of membrane rigidity [PDF]

, 2020
Mitochondria have been widely accepted as the main source of ATP in the cell. The inner mitochondrial membrane (IMM) is important for the maintenance of ATP production and other functions of mitochondria.
Arieli, Baranov, Bazil, Bazil, Beavis, Bernardi, Bernardi, Bernardi, Brenner, Carraro, Carroll, Chapa-Dubocq, Crockett, Giorgi, Griffiths, Halestrap, Halestrap, Halestrap, Halestrap, Hollander, Holmuhamedov, Hoppe, Ichas, Ichas, Igor Khmelinskii, Javadov, Javadov, Javadov, Kirichok, Kuznetsov, Kwong, Ladbrooke, Lehninger, Lopez-Crisosto, Makarov, Massari, O'Rourke, Palmer, Petronilli, Pokhilko, Sabzali Javadov, Scalettar, Selivanov, Shinitzky, Song, Szabo, Vladimir I. Makarov, Wodtke, Zaza Khuchua   +48 more
core   +1 more source

Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer

Journal of Translational Medicine, 2023
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu, Zhi Lv, Zi-wei Yan, Xiao-yang Wu, Li-rong Yan, Li-ping Sun, Yuan Yuan, Qian Xu   +7 more
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Mitochondrial Dynamics: A Key Role in Neurodegeneration and a Potential Target for Neurodegenerative Disease

Frontiers in Neuroscience, 2021
In neurodegenerative diseases, neurodegeneration has been related to several mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria, impaired mitophagy, and blocked mitochondria mitochondrial transport in axons.
Danying Yang, Danying Yang, Jun Ying, Jun Ying, Xifeng Wang, Tiancheng Zhao, Sungtae Yoon, Yang Fang, Yang Fang, Qingcui Zheng, Qingcui Zheng, Xing Liu, Xing Liu, Wen Yu, Wen Yu, Fuzhou Hua, Fuzhou Hua   +16 more
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Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

Membranes, 2022
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi, Azza Salah, Ayman W. El-Hattab   +2 more
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AMPKα2 Overexpression Reduces Cardiomyocyte Ischemia-Reperfusion Injury Through Normalization of Mitochondrial Dynamics

Frontiers in Cell and Developmental Biology, 2020
Cardiac ischemia-reperfusion (I/R) injury is associated with mitochondrial dysfunction. Recent studies have reported that mitochondrial function is determined by mitochondrial dynamics.
Yuanyan Deng, Sainan Chen, Mingming Zhang, Chen Li, Jing He, Ying Tan   +5 more
doaj   +1 more source

Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases [PDF]

, 2009
Neurons are metabolically active cells with high energy demands at locations distant from the cell body. As a result, these cells are particularly dependent on mitochondrial function, as reflected by the observation that diseases of mitochondrial ...
Alexander, Baloyannis, Banchs, Bossy-Wetzel, Brockmann, Cassidy-Stone, Chang, Chen, Cho, Clark, D. C. Chan, de Brito, Delettre, Dodson, Exner, Fransson, Frezza, Gispert, H. Chen, Hollenbeck, Kim, Kim, Li, Liot, Lustbader, Macaskill, Meeusen, Milone, Mortiboys, Okamoto, Orr, Park, Parone, Popp, Reis, Suen, Ten Dijke, Trushina, Wang, Waterham, Wood-Kaczmar, Zuchner, Z  chner   +42 more
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Effects of fission and mitophagy on mitochondrial functionality under accelerated damage conditions: A mathematical modeling approach

Frontiers in Applied Mathematics and Statistics, 2023
There is growing evidence that mitochondrial dynamics play a role in mitochondrial function quality control. Recent studies have discovered that physical activity can aid in maintaining a healthy mitochondrial population and may even counteract the ...
Ángel J. Zamora-Ramírez, Moisés Santillán   +1 more
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