Roles of mitochondrial fusion and fission in breast cancer progression: a systematic review [PDF]
World Journal of Surgical Oncology, 2022 Background Mitochondria play critical roles in cellular physiological activity as cellular organelles. Under extracellular stimulation, mitochondria undergo constant fusion and fission to meet different cellular demands. Mitochondrial dynamics, which are
Jixiang Xing +5 more
doaj +2 more sources
Mitochondrial morphological features are associated with fission and fusion events. [PDF]
PLoS ONE, 2014 Mitochondria are dynamic organelles that undergo constant remodeling through the regulation of two opposing processes, mitochondrial fission and fusion.
Laura M Westrate +4 more
doaj +4 more sources
The Role of Abnormal Mitochondrial Fusion and Fission in the Inflammatory Senescence of Dental Pulp Stem Cells [PDF]
International Dental JournalAim: The regeneration ability of dental pulp stem cells (DPSCs) is essential for vital pulp preservation therapy, but may be disrupted by inflammatory senescence.
Wenyue Tang +9 more
doaj +2 more sources
Mitochondrial fission and fusion in inflammatory diseases: mechanisms and therapeutic implications [PDF]
Journal of Translational MedicineBackground Mitochondrial fission and fusion are dynamic and highly regulated processes that are essential for maintaining cellular homeostasis. These processes are regulated by core proteins, including dynamin-related protein 1 (DRP1), fission 1 protein (
Wenjing Xu +4 more
doaj +2 more sources
Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders
Membranes, 2022 Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi +2 more
doaj +1 more source
BMC Biology, 2021 Background Mitochondrial dynamics is the result of a dynamic balance between fusion and fission events, which are driven via a set of mitochondria-shaping proteins.
Rong Yu +6 more
doaj +1 more source
The Imbalance of Mitochondrial Fusion/Fission Drives High-Glucose-Induced Vascular Injury
Biomolecules, 2021 Emerging evidence shows that mitochondria fusion/fission imbalance is related to the occurrence of hyperglycemia-induced vascular injury. To study the temporal dynamics of mitochondrial fusion and fission, we observed the alteration of mitochondrial ...
Yunsi Zheng, Anqi Luo, Xiaoquan Liu
doaj +1 more source
Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteins. [PDF]
PLoS ONE, 2011 Mitochondria in mammals are organized into tubular networks that undergo frequent shape change. Mitochondrial fission and fusion are the main components mediating the mitochondrial shape change.
Pinwei Huang +2 more
doaj +1 more source
Cells, 2023 Mitochondria, which generate ATP through aerobic respiration, also have important noncanonical functions. Mitochondria are dynamic organelles, that engage in fission (division), fusion (joining) and translocation. They also regulate intracellular calcium
Pierce Colpman +2 more
doaj +1 more source
Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance. [PDF]
PLoS ONE, 2013 Accumulation of mitochondrial DNA (mtDNA) mutations has been implicated in a wide range of human pathologies, including neurodegenerative diseases, sarcopenia, and the aging process itself.
Zhi Yang Tam +3 more
doaj +1 more source