Results 61 to 70 of about 29,418 (143)

Mitochondrial event localiser (MEL) to quantitativelydescribe fission, fusion and depolarisation in the three-dimensional space.

PLoS ONE, 2020
Mitochondrial fission and fusion play an important role not only in maintaining mitochondrial homeostasis but also in preserving overall cellular viability.
Rensu P Theart, Jurgen Kriel, André du Toit, Ben Loos, Thomas R Niesler   +4 more
doaj   +1 more source

Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem Cells

Frontiers in Cell and Developmental Biology, 2020
Mesenchymal stem cells (MSCs) are pivotal to tissue homeostasis, repair, and regeneration due to their potential for self-renewal, multilineage differentiation, and immune modulation.
Lin Ren, Lin Ren, Lin Ren, Xiaodan Chen, Xiaodan Chen, Xiaodan Chen, Xiaobing Chen, Xiaobing Chen, Xiaobing Chen, Jiayan Li, Jiayan Li, Jiayan Li, Bin Cheng, Bin Cheng, Bin Cheng, Juan Xia, Juan Xia, Juan Xia   +17 more
doaj   +1 more source

Emergence of the Mitochondrial Reticulum from Fission and Fusion Dynamics

PLoS Computational Biology, 2012
Mitochondria form a dynamic tubular reticulum within eukaryotic cells. Currently, quantitative understanding of its morphological characteristics is largely absent, despite major progress in deciphering the molecular fission and fusion machineries shaping its structure. Here we address the principles of formation and the large-scale organization of the
Sukhorukov, Valerii M., Dikov, Daniel, Reichert, Andreas, Meyer-Hermann, Michael (Prof. Dr.)   +3 more
openaire   +6 more sources

Mitochondrial dynamism and heart disease: changing shape and shaping change

EMBO Molecular Medicine, 2015
Mitochondria of adult cardiomyocytes appear hypo‐dynamic, lacking interconnected reticular networks and the continual fission and fusion observed in many other cell types.
Gerald W Dorn
doaj   +1 more source

Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

Redox Biology, 2017
Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabetes is
Susana Rovira-Llopis, Celia Bañuls, Noelia Diaz-Morales, Antonio Hernandez-Mijares, Milagros Rocha, Victor M. Victor   +5 more
doaj   +1 more source

Skeletal muscle mitochondrial bioenergetics and morphology in high fat diet induced obesity and insulin resistance: focus on dietary fat source

Frontiers in Physiology, 2016
It has been suggested that skeletal muscle mitochondria play a key role in high fat diet induced insulin resistance. Two opposite views are debated on mechanisms by which mitochondrial function could be involved in skeletal muscle insulin resistance.
Rosalba ePutti, Vincenzo eMigliaccio, Raffaella eSica, Lillà eLionetti   +3 more
doaj   +1 more source

Endoplasmic reticulum stress induced by turbulence of mitochondrial fusion and fission was involved in stressed cardiomyocyte injury. [PDF]

J Cell Mol Med, 2023
Zhang S, Li Y, Zhu W, Zhang L, Lei L, Tian X, Chen K, Shi W, Cong B.   +8 more
europepmc   +1 more source

Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover

Antioxidants, 2018
The mitochondrial network is a dynamic organization within eukaryotic cells that participates in a variety of essential cellular processes, such as adenosine triphosphate (ATP) synthesis, central metabolism, apoptosis and inflammation.
Sumaira Ali, Gavin P. McStay
doaj   +1 more source

Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance. [PDF]

Int J Biol Sci, 2023
Lai Q, Wu L, Dong S, Zhu X, Fan Z, Kou J, Liu F, Yu B, Li F.   +8 more
europepmc   +1 more source

Quantification of Mitochondrial Dynamics in Fission Yeast

Bio-Protocol, 2019
Mitochondria are double-membraned organelles responsible for several functions in the cell including energy production, calcium signaling, and cellular metabolism.
Leeba Chacko, Vaishnavi Ananthanarayanan
doaj   +1 more source