Results 71 to 80 of about 53,504 (295)

Bioactive Conductive Ti3C2Tx‐Ce Hydrogel Facilitates Spinal Cord Injury Repair Through ROS Scavenging and Mitochondrial Regulation

Advanced Functional Materials, EarlyView.
Bioactive conductive Ti3C2Tx‐Ce hydrogels with with scavenging ROS and alleviating neuronal mitochondrial dysfunction are exploited for SCI treatment. This functionality is attributed to interfacial activation modification of Ti3C2Tx with Ce3+ ions to in‐situ form Ce(OH)x‐mediated protective layer, which is beneficial to enabling stable intracellular ...
Weikang Wang, Qing Liu, Ang Lv, Yabin Lin, Jiawei Chen, Ning Ding, Chunlei Zhang, Shuai Zhou, Bo Yuan, Weiwei Zhao, Liming Li, Luping Zhang, Fei Huang   +12 more
wiley   +1 more source

The effects of different exercise training protocols on mitochondrial dynamics in skeletal and cardiac muscles of Wistar rats

Journal of Orthopaedic Surgery and Research
Background Mitochondrial fission and fusion both contribute to maintaining mitochondrial function and optimizing bioenergetic capacity. Objective The aim of this study was to compare the effect of aerobic and resistance training on mitochondrial fission ...
Amir Hossein Haghighi, Mohammad Reza Bandali, Roya Askari, Hadi Shahrabadi, Rosario Barone, Roberto Bei, Pasquale Farsetti, Marco Alfonso Perrone   +7 more
doaj   +1 more source

Multi-patterned dynamics of mitochondrial fission and fusion in a living cell. [PDF]

PLoS ONE, 2012
Mitochondria are highly-dynamic organelles, but it is challenging to monitor quantitatively their dynamics in a living cell. Here we developed a novel approach to determine the global occurrence of mitochondrial fission and fusion events in living human ...
Shiqi Wang, Weiming Xiao, Sicong Shan, Chunsun Jiang, Ming Chen, Yan Zhang, Shouqin Lü, Juan Chen, Chuanmao Zhang, Quan Chen, Mian Long   +10 more
doaj   +1 more source

Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

, 2018
Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the synthesis of macromolecules and ...
Pearce, E., Rambold, A.
core   +1 more source

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane. [PDF]

, 2018
Mitochondria are cellular organelles with crucial functions in the generation and distribution of ATP, the buffering of cytosolic Ca2+ and the initiation of apoptosis. Compounds that interfere with these functions are termed mitochondrial toxins, many of
Anand, Ruchika, Barbian, Andreas, Berleth, Niklas, Borchardt, Andrea, Böhler, Philip, Böhler, Philip, Deitersen, Jana, Frank, Marian, García-Sáez, Ana J, Itskanov, Samuel, Kondadi, Arun Kumar, Luyten, Tomas, Niemann, Hendrik, Parys, Jan B, Peña-Blanco, Aida, Proksch, Peter, Reichert, Andreas S, Schlütermann, David, Stork, Björn, Stuhldreier, Fabian, van der Bliek, Alexander M, Wallot-Hieke, Nora, Weidtkamp-Peters, Stefanie, Wesbuer, Elisabeth, Wesselborg, Sebastian, Wu, Wenxian   +25 more
core   +2 more sources

Organelle Localization‐Induced Bio‐Orthogonal Polymerization (OLIBOP) for Photostable Super‐Resolution Live‐Cell Imaging

Advanced Healthcare Materials, EarlyView.
Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park, Sangpil Kim, Dohyun Kim, Injun Hwang, Ja‐Hyoung Ryu   +4 more
wiley   +1 more source

Mitochondrial dynamics and colorectal cancer biology: mechanisms and potential targets

Cell Communication and Signaling
Colorectal cancer (CRC) is a significant public health concern, and its development is associated with mitochondrial dysfunction. Mitochondria can adapt to the high metabolic demands of cancer cells owing to their plasticity and dynamic nature.
Zihong Wu, Chong Xiao, Jing Long, Wenbo Huang, Fengming You, Xueke Li   +5 more
doaj   +1 more source

Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease

Neurobiology of Disease, 2013
Nascent evidence indicates that mitochondrial fission, fusion, and transport are subject to intricate regulatory mechanisms that intersect with both well-characterized and emerging signaling pathways.
Theodore J. Wilson, Andrew M. Slupe, Stefan Strack   +2 more
doaj   +1 more source

Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration [PDF]

, 2018
Research efforts during the last decade have deciphered the basic molecular mechanisms governing mitochondrial fusion and fission. We now know that in mammalian cells mitochondrial fission is mediated by the large GTPase dynamin-related protein 1 (Drp1 ...
Frank, Stephan, Licci, Maria, Oettinghaus, Björn, Scorrano, Luca   +3 more
core  

Proteolytic Processing of OPA1 Links Mitochondrial Dysfunction to Alterations in Mitochondrial Morphology [PDF]

, 2006
Many muscular and neurological disorders are associated with mitochondrial dysfunction and are often accompanied by changes in mitochondrial morphology.
Attardi, Giuseppe, Bauer, Matthis F., Chomyn, Anne, Duvezin-Caubet, Stéphane, Hansson, Anna, Hofmann, Sabine, Jagasia, Ravi, Larsson, Nils-Göran, Neupert, Walter, Reichert, Andrea S., Trifunovic, Aleksandra, Wagener, Johannes   +11 more
core   +2 more sources