Results 41 to 50 of about 2,942 (230)
The dark web trades wildlife, but mostly for use as drugs
People and Nature, Volume 5, Issue 3, Page 999-1009, June 2023., 2023 Abstract Contemporary wildlife trade is massively facilitated by the Internet. By design, the dark web is one layer of the Internet that is difficult to monitor and continues to lack thorough investigation. Here, we accessed a comprehensive database of dark web marketplaces to search across c. 2 million dark web advertisements over 5 years using c. 7 k
Oliver C. Stringham +14 more
wiley +1 more source
Frontiers in Pharmacology, 2021 Multiorgan toxicities have been extensively reported in kratom (Mitragyna speciosa Korth) users in Western countries but not in Southeast Asia. Existing literature argued that this discrepancy may be due to underreporting of kratom-related toxicity cases
Mohammad Farris Iman Leong Bin Abdullah +1 more
doaj +1 more source
Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
core +1 more source
Clinical and Translational Science, Volume 16, Issue 6, Page 1002-1011, June 2023., 2023 Abstract Kratom is a widely used Asian botanical that has gained popularity in the United States due to a perception that it can treat pain, anxiety, and opioid withdrawal symptoms. The American Kratom Association estimates 10–16 million people use kratom.
Xiaotong Li +8 more
wiley +1 more source
Molecules, 2015 Varied pharmacological responses have been reported for mitragynine in the literature, but no supportive scientific explanations have been given for this.
Surash Ramanathan +5 more
doaj +1 more source
PLoS ONE, 2023 Regular use of Thai kratom has been linked to reduced blood triglyceride levels and body mass index (BMI) in healthy individuals. We analyzed Green Thai Kratom (GTK) and Red Thai Kratom (RTK) to investigate their effects on pancreatic digestive enzymes ...
Atikarn Janthongkaw +7 more
doaj +1 more source
Drug testing for mitragynine and kratom: Analytical challenges and medico‐legal considerations
Drug Testing and Analysis, Volume 15, Issue 2, Page 213-219, February 2023., 2023 The use of kratom, that is, leaves from the Southeast Asian tree Mitragyna speciosa, has spread to the Western world. Kratom contain several alkaloids including mitragynine and its three diastereomers mitraciliatine, speciogynine and speciociliatine. In Sweden, only mitragynine is classified.
Anders Helander, Alexia Rylski
wiley +1 more source
Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]
, 2017 A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow +8 more
core +1 more source
MedComm, Volume 3, Issue 3, September 2022., 2022 1. Rewarding effects and withdrawal syndrome are two dominant components of opioid addiction. 2. Mu‐opioid receptors (MORs) are highly involved in reward circuitry and the development of withdrawal syndrome. 3. MORs are important targets to treat addiction and withdrawal syndrome.
Jia‐Jia Zhang +5 more
wiley +1 more source
Indolo[2,3-a]quinolizidines and derivatives: Bioactivity and asymmetric Synthesis [PDF]
, 2016 Corynantheine alkaloids with a tetracyclic indole[2,3-a]-quinolizidine motif are an important issue in academia and in the life science industries due to their broad bioactivity profile.
Espadinha, Margarida +2 more
core +1 more source