Results 41 to 50 of about 2,217 (207)
Frontiers in Pharmacology, 2021 Background: Kratom (Mitragyna speciosa Korth), a popular opioid-like plant holds its therapeutic potential in pain management and opioid dependence. However, there are growing concerns about the safety or potential toxicity risk of kratom after prolonged
Thenmoly Damodaran +4 more
doaj +1 more source
PLoS ONE, 2023 Regular use of Thai kratom has been linked to reduced blood triglyceride levels and body mass index (BMI) in healthy individuals. We analyzed Green Thai Kratom (GTK) and Red Thai Kratom (RTK) to investigate their effects on pancreatic digestive enzymes ...
Atikarn Janthongkaw +7 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Multiorgan toxicities have been extensively reported in kratom (Mitragyna speciosa Korth) users in Western countries but not in Southeast Asia. Existing literature argued that this discrepancy may be due to underreporting of kratom-related toxicity cases
Mohammad Farris Iman Leong Bin Abdullah +1 more
doaj +1 more source
Effects of mitragynine from Mitragyna speciosa Korth leaves on working memory [PDF]
, 2010 Aim of the study: Mitragyna speciosa Korth from Rubiaceae family is a tropical plant indigenous to Southeast Asia particularly in Thailand, Peninsular of Malaysia and Indonesia. The leaves have been used by natives for their opium-like effect and cocaine-
Apryani, Evhy +4 more
core +1 more source
Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]
, 2017 A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow +8 more
core +1 more source
Changing Trends in the Use of Kratom (Mitragyna speciosa) in Southeast Asia [PDF]
, 2017 This is the pre-peer reviewed version of the following article: Darshan Singh, Suresh Narayanan, Balasingam Vicknasingam, Ornella Corazza, Rita Santacroce, and Andres Roman-Urrestarazu, ‘Changing trends in the use of kratom (Mitragyna speciosa) in ...
Corazza, Ornella +5 more
core +2 more sources
Urine Screening for Opiod and Illicit Drugs in the Total Joint Arthroplasty Population [PDF]
, 2020 Introduction. Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery.
Bhargava, Tarun +6 more
core +2 more sources
Discovery of a Plant Pictet–Spenglerase With R‐Stereoselectivity
Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.Strictosidine synthases (STRs) are plant Pictet–Spenglerases catalyzing the coupling of a secoiridoid with tryptamine. All previously characterized strictosidine synthases are strictly S‐selective. Here, we report the discovery of Epi‐STR, an R‐selective STR ortholog from the medicinal plant Pogonopus speciosus.
Clara Morweiser +3 more
wiley +2 more sources
Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products
Life, 2022 Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation.
Islamudin Ahmad +18 more
doaj +1 more source
Indolo[2,3-a]quinolizidines and derivatives: Bioactivity and asymmetric Synthesis [PDF]
, 2016 Corynantheine alkaloids with a tetracyclic indole[2,3-a]-quinolizidine motif are an important issue in academia and in the life science industries due to their broad bioactivity profile.
Espadinha, Margarida +2 more
core +1 more source