Results 101 to 110 of about 14,072 (183)

MLKL wt Allele [PDF]

, 2020
openaire   +1 more source

Genomic and Transcriptional Analysis of the Necroptosis Pathway Elements RIPK and MLKL in Sea Cucumber, Holothuria leucospilota

Background: Receptor-interacting protein kinases (RIPKs) and mixed-lineage kinase domain-like protein (MLKL) are crucial in regulating innate immune responses and cell death signaling (necroptosis and apoptosis), and are potential candidates for genetic ...
Shuangxin Peng, Xiaoli Zhang, Ting Chen, Aifen Yan, Qianying Huang, Xiangxing Zhu, Tiehao Lin, Yingzhu Rao, Dongsheng Tang, Yihang Huang, Ruiming Yu, Rong Chen, Kaiyi Huang, Junyan Wang   +13 more
core   +1 more source

TNF-induced lethality occurs independently of NLRP3 inflammasome signaling. [PDF]

Signal Transduct Target Ther
Riebeling T, von Samson-Himmelstjerna FA, Kolbrink B, Schmitt R, Krautwald S.   +4 more
europepmc   +1 more source

Necroptosis: MLKL Polymerization.

, 2018
Necroptosis is a subtype of regulated necrosis that occurs when caspases are inhibited or fail to activate. Stimulus of cell death receptors results in a signaling cascade that triggers caspase independent, immunogenic cell death. The core pathway relies
Johnston, Andrea
core  

MLKL regulates intracellular trafficking of neutrophil elastase to promote lung epithelial cell senescence. [PDF]

Am J Respir Cell Mol Biol
Liu R, Zhang A, Shapiro SD, Chen D.
europepmc   +1 more source

Lytic cell death in chronic lung diseases. [PDF]

Am J Respir Cell Mol Biol
Siokas I, Heileman M, Fritz LC, Degterev A.   +3 more
europepmc   +1 more source

A Marine Bivalve (<i>Entodesma navicula</i>) Extract Suppresses the Replication of Influenza Viruses and Flaviviruses in Association with Reduced MLKL Phosphorylation. [PDF]

Animals (Basel)
Moon HJ, Lee G, Ko SC, Lee JM, Kim JY, Yim MJ, Choi J, Lee CD, Lee JB, Park JG, Baek YB, Park SI.   +11 more
europepmc   +1 more source

Suppression of Calpain Attenuates Coxsackievirus B3-Induced Myocarditis by Regulating RIPK1/RIPK3/MLKL Pathway. [PDF]

J Cardiovasc Transl Res
Liu Y, Wang Y, Liu G, Yi F, Che D, Chen Z, Zou Y, Chen R.   +7 more
europepmc   +1 more source

z-VAD-FMK triggers macrophage necroptosis during mycobacterial infection via a non-canonical off-target mechanism. [PDF]

mLife
Hu R, Li P, Han J, Huang J, Huang G, Jiang X, Pfau D, Li G, Gong YN, Nathan CF, Zhang L.   +10 more
europepmc   +1 more source

Transcript-Level Expression Patterns of Necroptosis-Related Genes RIPK1, RIPK3, and MLKL in Surgically Resected Non-Small Cell Lung Cancer: An Exploratory Single-Center Study. [PDF]

Int J Mol Sci
Ulugun FI, Yavuzşen T, Aktaş S, Altun ZS, Özdemir N, Ömeroğlu Şimşek G, Gürel D, Baran B, Arayici ME.   +8 more
europepmc   +1 more source