Results 111 to 120 of about 13,855 (152)

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. [PDF]

Elife
Rincon-Torroella J, Dal Molin M, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad N, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, Gabrielson K, Sur S.   +16 more
europepmc   +1 more source

A Phase I Dose-escalation Study of AZD3965, an Oral Monocarboxylate Transporter 1 Inhibitor, in Patients with Advanced Cancer. [PDF]

Clin Cancer Res, 2023
Halford S, Veal GJ, Wedge SR, Payne GS, Bacon CM, Sloan P, Dragoni I, Heinzmann K, Potter S, Salisbury BM, Chénard-Poirier M, Greystoke A, Howell EC, Innes WA, Morris K, Plummer C, Rata M, Petrides G, Keun HC, Banerji U, Plummer R.   +20 more
europepmc   +1 more source

Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP-mediated transrepression pathway. [PDF]

MedComm (2020)
Li Z, Guo S, Cao K, Duan Y, Zhao Y, Zhang Y, Yu S, Bai Z, Yu R, Chen Y, Li Z, Huang S, Song M, Wang C, Hou W, He J, Yang B, Xu Y.   +17 more
europepmc   +1 more source

Utilizing Monocarboxylate Transporter 1-Mediated Blood-Brain Barrier Penetration for Glioblastoma Positron Emission Tomography Imaging with 6-[¹⁸F]Fluoronicotinic Acid. [PDF]

Mol Pharm
Dillemuth P, Ayo A, Airenne TT, Lövdahl P, Bakay E, Zhuang X, Liljenbäck H, Paunonen ST, Kunnas J, Filppu P, Rajander J, Johnson MS, Roivainen A, Salminen TA, Rosenholm JM, Laakkonen P, Li XG.   +16 more
europepmc   +1 more source

Unmet patient needs in monocarboxylate transporter 8 (MCT8) deficiency: a review. [PDF]

Front Pediatr
Bauer AJ, Auble B, Clark AL, Hu TY, Isaza A, McNerney KP, Metzger DL, Nicol L, Pierce SR, Sidlow R.   +9 more
europepmc   +1 more source

The Predictive Value of Monocarboxylate Transporter 4 (MCT4) on Lung Adenocarcinoma Patients Treated with PD-1 Inhibitors. [PDF]

J Inflamm Res
Zhang Q, Pan G, Zhang L, Xu Y, Hao J.
europepmc   +1 more source

Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8. [PDF]

Int J Mol Sci
Anthofer L, Gmach P, Uretmen Kagiali ZC, Kleinau G, Rotter J, Opitz R, Scheerer P, Beck-Sickinger AG, Wolf P, Biebermann H, Bechmann I, Kühnen P, Krude H, Paisdzior S.   +13 more
europepmc   +1 more source

Combined Levothyroxine and Propylthiouracil Treatment in Children with Monocarboxylate Transporter 8 Deficiency: A Multicenter Case Series of 12 Patients. [PDF]

Thyroid
Weiss RE, Lemos JRN, Dumitrescu AM, Islam MS, Hirani K, Refetoff S.   +5 more
europepmc   +1 more source

Disruption of the Physical Interaction Between Carbonic Anhydrase IX and the Monocarboxylate Transporter 4 Impacts Lactate Transport in Breast Cancer Cells. [PDF]

Int J Mol Sci
Combs JE, Murray AB, Lomelino CL, Mboge MY, Mietzsch M, Horenstein NA, Frost SC, McKenna R, Becker HM.   +8 more
europepmc   +1 more source

Hippocampal Lactate-Infusion Enhances Spatial Memory Correlated with Monocarboxylate Transporter 2 and Lactylation. [PDF]

Brain Sci
Wu Y, Hu H, Liu W, Zhao Y, Xie F, Sun Z, Zhang L, Dong H, Wang X, Qian L.   +9 more
europepmc   +1 more source