Results 121 to 130 of about 13,009 (197)

Targeting cancer lactate metabolism with synergistic combinations of synthetic catalysts and monocarboxylate transporter inhibitors. [PDF]

J Biol Inorg Chem, 2023
Bridgewater HE, Bolitho EM, Romero-Canelón I, Sadler PJ, Coverdale JPC.   +4 more
europepmc   +1 more source

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. [PDF]

Elife
Rincon-Torroella J, Dal Molin M, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad N, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, Gabrielson K, Sur S.   +16 more
europepmc   +1 more source

A Phase I Dose-escalation Study of AZD3965, an Oral Monocarboxylate Transporter 1 Inhibitor, in Patients with Advanced Cancer. [PDF]

Clin Cancer Res, 2023
Halford S, Veal GJ, Wedge SR, Payne GS, Bacon CM, Sloan P, Dragoni I, Heinzmann K, Potter S, Salisbury BM, Chénard-Poirier M, Greystoke A, Howell EC, Innes WA, Morris K, Plummer C, Rata M, Petrides G, Keun HC, Banerji U, Plummer R.   +20 more
europepmc   +1 more source

Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP-mediated transrepression pathway. [PDF]

MedComm (2020)
Li Z, Guo S, Cao K, Duan Y, Zhao Y, Zhang Y, Yu S, Bai Z, Yu R, Chen Y, Li Z, Huang S, Song M, Wang C, Hou W, He J, Yang B, Xu Y.   +17 more
europepmc   +1 more source

Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina. [PDF]

Invest Ophthalmol Vis Sci, 2022
Bisbach CM, Hass DT, Thomas ED, Cherry TJ, Hurley JB.   +4 more
europepmc   +1 more source

Utilizing Monocarboxylate Transporter 1-Mediated Blood-Brain Barrier Penetration for Glioblastoma Positron Emission Tomography Imaging with 6-[¹⁸F]Fluoronicotinic Acid. [PDF]

Mol Pharm
Dillemuth P, Ayo A, Airenne TT, Lövdahl P, Bakay E, Zhuang X, Liljenbäck H, Paunonen ST, Kunnas J, Filppu P, Rajander J, Johnson MS, Roivainen A, Salminen TA, Rosenholm JM, Laakkonen P, Li XG.   +16 more
europepmc   +1 more source

A monocarboxylate transporter-dependent mechanism confers resistance to exercise-induced fatigue in a high-altitude hypoxic environment. [PDF]

Sci Rep, 2023
Gao C, Yang B, Li Y, Pei W.
europepmc   +1 more source

Monocarboxylate Transporter 1 Hyperinsulinism [PDF]

, 2020
openaire   +1 more source

TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer. [PDF]

Int J Cancer, 2023
Roche ME, Ko YH, Domingo-Vidal M, Lin Z, Whitaker-Menezes D, Birbe RC, Tuluc M, Győrffy B, Caro J, Philp NJ, Bartrons R, Martinez-Outschoorn U.   +11 more
europepmc   +1 more source

Mammalian monocarboxylate transporter 7 (MCT7/Slc16a6) is a novel facilitative taurine transporter. [PDF]

J Biol Chem, 2022
Higuchi K, Sugiyama K, Tomabechi R, Kishimoto H, Inoue K.   +4 more
europepmc   +1 more source