Results 101 to 110 of about 13,009 (197)

Skeletal muscle phenotype of breath‐hold divers reveals adaptations towards metabolic efficiency under hypoxia

The Journal of Physiology, EarlyView.
Anthony Richard Bain
wiley   +1 more source

Repeatability of Metabolic Imaging With Hyperpolarized Pyruvate: Back‐to‐Back Neuroimaging and Blood Analysis

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 548-556, August 2026.
ABSTRACT Purpose 13C MRI with hyperpolarized [1‐13C]pyruvate enables noninvasive imaging of metabolic pathways. Considering the high dose of pyruvate used in hyperpolarized 13C‐pyruvate studies, circulating 13C‐pyruvate and the resulting 13C‐lactate in plasma may influence subsequent pyruvate metabolism, yet the guidance on consecutive injections does ...
Jun Chen, Sung‐Han Lin, Jessica Sudderth, Kelley A. Derner, Crystal E. Harrison, Maheen Zaidi, Jeannie D. Baxter, Jeff Liticker, Zohreh Erfani, Craig R. Malloy, Marco C. Pinho, Ralph J. DeBerardinis, Jae Mo Park   +12 more
wiley   +1 more source

GHB toxicokinetics and renal monocarboxylate transporter expression are influenced by the estrus cycle in rats. [PDF]

BMC Pharmacol Toxicol, 2023
Wei H, Cao J, Fallert T, Yeo S, Felmlee MA.   +4 more
europepmc   +1 more source

Activation of the Lactate Receptor GPR81 Ameliorates Senescence Hallmarks and Improves Muscle Function in Cellular and Progeroid Models of Aging

Aging Cell, Volume 25, Issue 8, August 2026.
Skeletal muscle aging is associated with a decrease in expression of the lactate receptor GPR81. Treating senescent myoblasts in vitro and progeric mice in vivo with GPR81 agonist decreases intramyocellular lipid accumulation and reverses hallmarks of aging. ABSTRACT Skeletal muscle aging is associated with increased lipid accumulation, or myosteatosis,
Pihu Mehrotra, Sai Harsha Bhamidipati, Pedro Lei, John Toftegaard, Debanik Choudhury, Maryam Elsayed, Yali Zhang, Jianmin Wang, Shweta Chitkara, G. Ekin Atilla‐Gokcumen, Song Liu, Stelios T. Andreadis   +11 more
wiley   +1 more source

Identification of drug repurposing candidates for the treatment of polycystic kidney disease

British Journal of Pharmacology, Volume 183, Issue 16, Page 5082-5101, August 2026.
Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer, Paraskevi Sotiropoulou, Koussai Bouker, Dennis Svedberg, Rebekkah Hammar, Hester Bange, Per Larsson, André Mateus, Daniel R. Dietrich, Per Artursson   +9 more
wiley   +1 more source

Effect of Sex and Cross-Sex Hormone Treatment on Renal Monocarboxylate-Transporter Expression in Rats. [PDF]

Pharmaceutics, 2023
Wei H, Lee A, Zhang Q, Felmlee MA.
europepmc   +1 more source

Monocarboxylate Transporter 3 [PDF]

, 2020
openaire   +1 more source

Monocarboxylate Transporter 13 (MCT13/SLC16A13) Functions as a Novel Plasma Membrane Oligopeptide Transporter. [PDF]

Nutrients, 2023
Higuchi K, Kunieda M, Sugiyama K, Tomabechi R, Kishimoto H, Inoue K.   +5 more
europepmc   +1 more source

Monocarboxylate Transporter 11 [PDF]

, 2020
openaire   +1 more source

Monocarboxylate Transporter 4 [PDF]

, 2020
openaire   +1 more source