Results 71 to 80 of about 113,465,300 (217)
Inborn Errors of Ketone Body Metabolism and Transport
Journal of Inborn Errors of Metabolism and Screening, 2018 Major progress occurred in understanding inborn errors of ketone body transport and metabolism between the International Congresses on Inborn Errors of Metabolism in Barcelona (2013) and Rio de Janeiro (2017).
Jörn Oliver Sass Dr. rer. nat. +2 more
doaj +1 more source
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
, 2021 monocarboxylate transporter-like protein | riboflavin transporter | RibJ Leishmania donovani (HU3 ...
Requena, J (via Mendeley Data) +1 more
core +1 more source
Increased Brain Monocarboxylic Acid Transport and Utilization in Type 1 Diabetes [PDF]
Diabetes, 2006 We hypothesized that increased capacity for brain utilization of nonglucose substrates (monocarboxylic acids [MCAs]) by upregulation of the MCA transporters may contribute metabolic substrates during hypoglycemia. To test this hypothesis, we assessed brain acetate metabolism in five well-controlled type 1 diabetic subjects and six nondiabetic control ...
Graeme F, Mason +4 more
openaire +2 more sources
Shikonin Promotes Apoptosis in Multiple Myeloma Cells Through the PKM2‐AMPK‐PGC1α Metabolic Axis
Journal of Clinical Laboratory Analysis, EarlyView.High PKM2 expression in MM is associated with a poor prognosis. Shikonin represents a promising PKM2‐targeted agent for MM therapy, offering a unique metabolic intervention strategy to improve drug resistance, bone disease, and the immune microenvironment. ABSTRACT Background Multiple myeloma (MM) is an incurable plasma malignancy.
Fengping Peng +7 more
wiley +1 more source
Oncologic impact of monocarboxylate transporter 4 (MCT4) in pancreatic cancer.
, 2015 319 Background: Transporters for monocarboxylate play an integral role in cancer metabolism in terms of the regulation of intracellular pH. The aim of our study is to check the oncologic impact of Monocarboxylate Transporter 4 (MCT4) expression in ...
Ho Kyoung Hwang +3 more
core +1 more source
Monocarboxylate transporter 1 and the vulnerability of oligodendrocyte lineage cells to metabolic stresses. [PDF]
CNS Neurosci Ther, 2018 SummaryAimsOligodendrocytes, especially oligodendrocyte precursor cells, are known to be sensitive to hypoxic and metabolic stresses. Vulnerability of oligodendrocytes is considered a contributing factor to white matter dysfunction. However, little is known about the energy processing characteristics of oligodendrocyte lineage cells under basal and ...
Zhou P +5 more
europepmc +4 more sources
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen +9 more
wiley +1 more source
, 2020 monocarboxylate transporter-like protein | riboflavin transporter | RibJ; Leishmania ...
Requena, J (via Mendeley Data) +1 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu +7 more
wiley +1 more source