Results 21 to 30 of about 28,651 (221)
Frontiers in Cell and Developmental Biology, 2023 Neural progenitors and their neuronal progeny are bathed in extrinsic signals that impact critical decisions like the mode of cell division, how long they should reside in specific neuronal laminae, when to differentiate, and the timing of migratory ...
Anna E. Pittman, David J. Solecki
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Travelling gradients in interacting morphogen systems [PDF]
, 2007 Morphogen gradients are well known to play several important roles in development; however the mechanisms underlying the formation and maintenance of these gradients are often not well understood.
Baker, Ruth E., Maini, P. K.
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Shaping Morphogen Gradients [PDF]
Cell, 2001 Supplemental Movie: Simulation of Gradient Formation in a Two-dimensional “Epithelium” around a Clone Impeding Morphogen MovementxDownload (4.59 MB ) Supplemental Movie: Simulation of Gradient Formation in a Two-dimensional “Epithelium” around a Clone Impeding Morphogen MovementThe simulation assumes that morphogen spreads by a random, nondirectional ...
Teleman, Aurelio A. +2 more
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Development of Morphogen Gradient: The Role of Dimension and Discreteness [PDF]
, 1995 The fundamental processes of biological development are governed by multiple signaling molecules that create non-uniform concentration profiles known as morphogen gradients.
Kolomeisky, Anatoly B., Teimouri, Hamid
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Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches [PDF]
, 2016 During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process.
Briscoe, James +3 more
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Precision of the Dpp gradient [PDF]
, 2008 Morphogen concentration gradients provide positional information by activating target genes in a concentration-dependent manner. Recent reports show that the gradient of the syncytial morphogen Bicoid seems to provide precise positional information to ...
Bollenbach, Tobias +5 more
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Cold Spring Harbor Perspectives in Biology, 2009 Nodal signals belong to the TGF-beta superfamily and are essential for the induction of mesoderm and endoderm and the determination of the left-right axis. Nodal signals can act as morphogens-they have concentration-dependent effects and can act at a distance from their source of production.
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Incorporating chemical signalling factors into cell-based models of growing epithelial tissues [PDF]
, 2011 In this paper we present a comprehensive computational framework within which the effects of chemical signalling factors on growing epithelial tissues can be studied. The method incorporates a vertex-based cell model, in conjunction with a solver for the
Baker, R. E. +3 more
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Mathematical models of morphogen gradients and their effects on gene expression [PDF]
, 2012 not ...
Baker, R. E., Shvartsman, S Y
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Journal of Developmental Biology, 2022 Intracellular signaling pathways are essential to establish embryonic patterning, including embryonic axis formation. Ectodermal patterning is also governed by a series of morphogens.
Tatsuo Michiue, Kohei Tsukano
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