Results 31 to 40 of about 28,651 (221)

Hormetic Electric Field Theory of Pattern Formation

open access: yesDose-Response, 2010
The hormetic morphogen theory of curvature ( Fosslien 2009 ) proposes that hormetic morphogen concentration gradients modulate the synthesis of adenosine triphosphate (ATP) by cells along the gradients (field cells) and thus regulate their proliferation ...
Egil Fosslien
doaj   +1 more source

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

open access: yeseLife, 2015
Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we ...
Julien Dubrulle   +6 more
doaj   +1 more source

Review on regulatory role of morphogens in the formation of dorsal-ventral pattern of vertebrate neural tube

open access: yes浙江大学学报. 农业与生命科学版, 2022
In vertebrates, the development of the central nervous system depends on the correct patterning of the neural tube along its anterior-posterior and dorsal-ventral axes in the early embryo as well as the underlying regulation of the cell differentiation ...
LIU Cong, XU Pengfei
doaj   +1 more source

Analysis of a Model Biological Switch [PDF]

open access: yes, 1985
A model mechanism proposed by Murray [Phil. Traps. Roy. Soc. London B, 295 (1981), pp. 473–496] for generating wing patterns and eyespots on butterflies and moths is based on a morphogen (S) activated biological switch for a gene product (g).
Kath, W. L., Murray, J. D.
core   +1 more source

Spatially Distributed Morphogen Production and Morphogen Gradient Formation

open access: yesMathematical Biosciences and Engineering, 2005
Partial diferential equations and auxiliary conditions governing the activities of the morphogen Dpp in Drosophila wing imaginal discs were formulated and analyzed as Systems B, R, and C in [7] [9] [10]. All had morphogens produced at the border of anterior and posterior chamber of the wing disc idealized as a point, line, or plane in a one-, two-, or ...
Arthur D. Lander   +2 more
openaire   +3 more sources

Patterning of the Drosophila retina by the morphogenetic furrow

open access: yesFrontiers in Cell and Developmental Biology, 2023
Pattern formation is the process by which cells within a homogeneous epithelial sheet acquire distinctive fates depending upon their relative spatial position to each other.
Jasmine Warren, Justin P. Kumar
doaj   +1 more source

An atlas of gene regulatory networks reveals multiple three‐gene mechanisms for interpreting morphogen gradients

open access: yesMolecular Systems Biology, 2010
The interpretation of morphogen gradients is a pivotal concept in developmental biology, and several mechanisms have been proposed to explain how gene regulatory networks (GRNs) achieve concentration‐dependent responses.
James Cotterell, James Sharpe
doaj   +1 more source

Well-posedness and asymptotic behavior of a multidimensional model of morphogen transport [PDF]

open access: yes, 2011
Morphogen transport is a biological process, occurring in the tissue of living organisms, which is a determining step in cell differentiation. We present rigorous analysis of a simple model of this process, which is a system coupling parabolic PDE with ...
A. Kicheva   +9 more
core   +2 more sources

The Hormetic Morphogen Theory of Curvature and the Morphogenesis and Pathology of Tubular and other Curved Structures

open access: yesDose-Response, 2009
In vitro, morphogens such as transforming growth factor (TGF)-β can up-and down-regulate cell growth at low and high concentrations respectively, i.e. they behave like hormetic agents.
Egil Fosslien
doaj   +1 more source

Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo

open access: yeseLife, 2017
Morphogen gradients provide essential spatial information during development. Not only the local concentration but also duration of morphogen exposure is critical for correct cell fate decisions.
Anqi Huang   +4 more
doaj   +1 more source

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