Results 81 to 90 of about 39,988 (211)

Effect of PEA on behavioural impairments induced by MPTP.

open access: yes, 2013
Catalepsy was evaluated according to the standard bar hanging procedure (A). In panel B results from Beam Trasversal test are reported. PEA treatment (10 mg/kg) reduced behavioural impairments induced by MPTP in WT mice, but in PPARαKO mice PEA didn't ...
Emanuela Esposito (286778)   +4 more
core   +1 more source

Tipping Points and Endogenous Determinants of Nigrostriatal Degeneration by MPTP

open access: yes, 2017
The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes a Parkinson's disease (PD)-like syndrome by inducing degeneration of nigrostriatal dopaminergic neurons.
Di Monte, Donato A.   +9 more
core   +1 more source

MPTP 0.1 - System Description

open access: yesElectronic Notes in Theoretical Computer Science, 2003
AbstractMPTP (Mizar Problems for Theorem Proving) is a system for translating the Mizar Mathematical Library (MML) into untyped first order format suitable for automated theorem provers, allowing generating theorem proving problems corresponding to MML.
openaire   +2 more sources

Mitochondrial permeability transition dictates mitochondrial maturation upon switch in cellular identity of hematopoietic precursors

open access: yesCommunications Biology
The mitochondrial permeability transition pore (mPTP) is a supramolecular channel that regulates exchange of solutes across cristae membranes, with executive roles in mitochondrial function and cell death.
Sandeep P. Dumbali   +3 more
doaj   +1 more source

Nigral dopaminergic neurons are protected against MPTP in ASK1−/− mice.

open access: yes, 2013
(A) Western blot for ASK1 in substantia nigra tissue lysates from wild-type and ASK1−/− mice shows loss of the specific band in the latter group (arrow). The asterisk marks a nonspecific band.
Teresa W. Chan (335663)   +10 more
core   +1 more source

Motor dysfunction assessment and numbers of TH positive neurons in the SNpc after MPTP treatment.

open access: yes, 2015
Body weights of mice during MPTP injection (5 consecutive days: A). *, compared to CON (rAAV-GFP+saline); +, compared to SYN (rAAV-α-syn+saline); #, compared to MPTP (rAAV-GFP+MPTP); SYN-MPTP (rAAV-α-syn+MPTP).
Kai-Li Ma (761834)   +7 more
core   +1 more source

Following MPTP treatment, the circadian locomotor rest-activity rhythm is abolished under constant light.

open access: yes, 2014
(A) Pre-MPTP treatment, daily locomotor activity is synchronized to the LD cycle (dark phase shown by shading) and in constant light (LL) the circadian rhythm free runs with a period of 23.97 hrs (Monkey Y).
Kwamivi Dzahini (513456)   +9 more
core   +1 more source

Exercise does not protect against MPTP-induced SN DA neurotoxicity in BDNF +/− mice.

open access: yes, 2013
(A) Representative photomicrograph of the SNpc of C57BL/6 mouse at the level of the medial longitundinal fasciculus (mlf). (B) Representative photomicrograph of the SNpc of BDNF+/− mouse at the level of the medial longitundinal fasciculus (mlf).
Yun Jiao (115357)   +3 more
core   +1 more source

PHLPP1 deficiency alleviates dopaminergic neurodegeneration and represses neuroinflammation in Parkinson’s disease

open access: yesBehavioral and Brain Functions
Background Pleckstrin homology (PH) domain leucine-rich repeat protein phosphatases (PHLPP) has been associated with several neurodegenerative diseases, however, few studies have investigated the role of PHLPP in Parkinson’s disease (PD).
Zhilin Chen   +7 more
doaj   +1 more source

Recovery of GIRK2 immunostaining in SNc of MPTP-treated mice.

open access: yes, 2015
A) Mice were treated for 4 days with daily injections of 25 mg/kg body weight of MPTP. The control group was injected with saline. After a 4-day rest period, MPTP-treated mice were split into 2 groups that were given by gavage 14 daily doses of either 2 ...
Olimpo García-Beltrán (836962)   +10 more
core   +1 more source

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