Results 31 to 40 of about 1,257,185 (207)
Zdorovʹe Rebenka, 2022 The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
doaj +1 more source
The link between adjacent codon pairs and mRNA stability
BMC Genomics, 2017 Background Evidence in diverse organisms suggests that codon optimality is a major determinant of mRNA translation and degradation. Codon optimality is thought to act by modulating the efficiency of ribosome elongation.
Yuriko Harigaya, Roy Parker
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Folate regulates RNA m5C modification and translation in neural stem cells
BMC Biology, 2022 Background Folate is an essential B-group vitamin and a key methyl donor with important biological functions including DNA methylation regulation. Normal neurodevelopment and physiology are sensitive to the cellular folate levels.
Xiguang Xu +5 more
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Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
doaj +1 more source
Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]
, 2007 Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E. +3 more
core +1 more source
Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs
Life Science Alliance, 2020 This study highlights the role of transglutaminase 2 in selective mRNA translation of hypoxic cancer cells by polyamination-dependent modulation of 4EBPs, providing a target for cancer treatment.
Sung-Yup Cho +12 more
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In vivo Imaging of oskar mRNA transport reveals the mechanism of posterior localization [PDF]
, 2008 oskar mRNA localization to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo. Although this localization requires microtubules and the plus end-directed motor, kinesin, its mechanism is controversial and ...
Zimyanin, Vitaly L +16 more
core +1 more source
Experimental characterization of Cis-acting elements important for translation and transcription in Halophilic Archaea [PDF]
, 2007 Summary The basal transcription apparatus of archaea is well characterized. However, much less is known about the mechanisms of transcription termination and translation initation.
Jörg Soppa +11 more
core +2 more sources
Respiratory syncytial virus (RSV) enhances translation of virus-resembling AU-rich host transcripts
Virology JournalBackground Viruses strongly rely on the host’s translational machinery to produce viral proteins required for replication. However, it is unknown how viruses that do not globally inhibit cap-dependent translation compete with abundant host transcripts ...
Kyra Kerkhofs +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source