Results 11 to 20 of about 2,567 (167)
Retinoblastoma and its binding partner MSI1 control imprinting in Arabidopsis. [PDF]
PLoS Biology, 2008 Parental genomic imprinting causes preferential expression of one of the two parental alleles. In mammals, differential sex-dependent deposition of silencing DNA methylation marks during gametogenesis initiates a new cycle of imprinting. Parental genomic
Pauline E Jullien +5 more
doaj +4 more sources
Msi1 inhibits cervical cancer cell apoptosis by downregulating BAK through AKT signaling [PDF]
Journal of Cancer, 2021 Musashi-1 (Msi1) is an RNA binding protein that functions as a regulator in multiple carcinomas. Our previous study demonstrated that Msi1 could promote the proliferation of cervical cancer cells by targeting the cell cycle proteins P21, P27 and P53. However, the mechanisms by which Msi1 affects the survival of cervical cancer cells, such as apoptosis,
Liu, Xian +3 more
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Regulation of flowering time byArabidopsis MSI1 [PDF]
Development, 2006 The transition to flowering is tightly controlled by endogenous programs and environmental signals. We found that MSI1 is a novel flowering-time gene in Arabidopsis. Both partially complemented msi1 mutants and MSI1 antisense plants were late flowering,whereas ectopic expression of MSI1 accelerated flowering.
Romaric, Bouveret +3 more
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Musashi1 inhibit the release of Newcastle disease viruses through preventing apoptosis of DF-1 cells
Poultry Science, 2021 : The efficient proliferation of Newcastle disease virus (NDV) depends on its inhibition of host cell innate immunity. V protein acts as a nonstructural protein which plays a significant role in virus replication, whereas its function remains to be ...
Mengqing Yang +11 more
doaj +1 more source
Functional Polymorphism in the MSI1 Gene Promoter Confers a Decreased Risk of Lung Cancer in Chinese by Reducing MSI1 Expression [PDF]
Current Genomics, 2018 Musashi1 (MSI1) is a characteristic stem cell marker that regulates the balance between cell self-renewal and differentiation. Evidence has identified MSI1 as a pivotal oncogenic regulator in diverse malignancies. However, little evidence uncovers the role of genetic variations of MSI1 gene in cancer etiology.The aim of this study was to investigate ...
Liu, Lin +6 more
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Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression in regenerating gastric mucosa. [PDF]
PLoS ONE, 2013 OBJECTIVE: Upregulation of the RNA-binding protein Musashi-1 (Msi1) has been shown to occur in rat gastric corpus mucosa after ethanol-induced mucosal injury. However, there is no direct evidence linking Msi1 with gastric regeneration.
Tetsufumi Takahashi +7 more
doaj +1 more source
The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma
Cells, 2021 Medulloblastoma is the most common malignant brain tumor in children. Treatment with surgery, irradiation, and chemotherapy has improved survival in recent years, but patients are frequently left with devastating neurocognitive and other sequelae ...
Mirella Baroni +8 more
doaj +1 more source
Mutual Interdependence of MSI1 (CAC3) and YAK1 in Saccharomyces cerevisiae [PDF]
Journal of Molecular Biology, 2007 The MSI1 (CAC3) gene of Saccharomyces cerevisiae has been implicated in diverse cellular functions, including suppression of the RAS/cAMP/protein kinase A signaling pathway, chromatin assembly and transcriptional co-repression. Seeking to identify the molecular mechanisms by which Msi1p carries out these distinct activities, a novel genetic interaction
Zachary L, Pratt +3 more
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World Journal of Surgical Oncology, 2021 Background Radiotherapy is a main therapeutic method for cancers, including colon cancer. In the current study, we aim to explore the effects of circular RNA (circRNA) circ_0055625 in the progression and radiosensitivity of colon cancer and the ...
Chao Gao +10 more
doaj +1 more source
Pleiotropic Roles of the Msi1-Like Protein Msl1 in Cryptococcus neoformans [PDF]
Eukaryotic Cell, 2012 ABSTRACT Msi1-like (MSIL) proteins contain WD40 motifs and have a pleiotropic cellular function as negative regulators of the Ras/cyclic AMP (cAMP) pathway and components of chromatin assembly factor 1 (CAF-1), yet they have not been studied in fungal pathogens. Here we identified and characterized an MSIL protein, Msl1, in
Dong-Hoon, Yang +6 more
openaire +2 more sources