Results 131 to 140 of about 21,251,406 (232)

UPLC‐QTOF‐MS/MS and Antifungal Activity of a Fraction Enriched in Saponins From Sarcomphalus joazeiro Against Candida spp

open access: yesBiomedical Chromatography, Volume 40, Issue 7, July 2026.
ABSTRACT The development of antifungal resistance is a complex process that involves the interaction between hosts, drugs, and microbial factors, all of which contribute to therapeutic ineffectiveness. For this reason, studies on natural products as possible therapeutic alternatives are increasingly necessary in order to gain a better understanding of ...
Ana Raquel Pereira da Silva   +12 more
wiley   +1 more source

Quantitative assessment of CBCT image quality metrics and their translation to clinical Art workflow performance in breast cancer patients

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.
Abstract Background Online adaptive radiotherapy (ART) relies on cone‐beam computed tomography (CBCT) imaging for daily treatment adaptation, but CBCT's physical limitations can compromise contour delineation and dose calculation accuracy. The relationship between image quality metrics and clinical ART workflow accuracy remains unclear.
Sunhwa Kim   +5 more
wiley   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

open access: yesAdvanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu   +7 more
wiley   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Facial injury management undertaken at US and UK medical treatment facilities during the Iraq and Afghanistan conflicts: a retrospective cohort study

open access: yesBMJ Open, 2019
Objectives To perform the first direct comparison of the facial injuries sustained and treatment performed at USA and UK deployed medical treatment facilities (MTFs) in support of the military campaigns in Iraq and Afghanistan.Setting The US and UK Joint
Douglas M Bowley   +6 more
doaj   +1 more source

Monitoring dolphinfish catches and diel assemblage fluctuations using eDNA at fish‐aggregating devices

open access: yesEcosphere, Volume 17, Issue 6, June 2026.
Abstract Fish‐aggregating devices (FADs) are man‐made objects designed to attract fish, with the aim of facilitating spatially heterogeneous aggregations of marine species. These objects influence the structure of pelagic fisheries, consequently affecting fish distributions and interactions. One of the most iconic epipelagic species targeted using FADs
N. Marinchel   +10 more
wiley   +1 more source

The Hepatitis C virus NS5A and core proteins exert antagonistic effects on HAMP gene expression: the hidden interplay with the MTF-1/MRE pathway. [PDF]

open access: yesFEBS Open Bio, 2021
Dimitriadis A   +9 more
europepmc   +1 more source

Structural and functional plasticity of metal-responsive transcription factor 1 (MTF-1) within Lophotrochozoa

open access: yesComparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
Control of metal ion metabolism in animals is crucial for their survival. In this context, the regulation of metallothioneins (MTs), key proteins in metal metabolism and detoxification, by the metal regulatory transcription factor MTF-1 is well established in vertebrates and Drosophila melanogaster.
Veronika, Pedrini-Martha   +4 more
openaire   +2 more sources

Encorafenib‐associated acantholytic dermatosis in collision with eccrine squamous syringometaplasia

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Francisco Meraz‐Torres   +5 more
wiley   +1 more source

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