Results 241 to 250 of about 102,812 (293)

Acute Responses and Chronic Adaptations to Cluster Versus Traditional Set Resistance Training in Males and Females

European Journal of Sport Science, Volume 26, Issue 4, April 2026.
ABSTRACT This study compared acute and chronic adaptations to cluster set (CS) and traditional set (TS) structures during a 6‐week linear periodised resistance training programme in the back squat. Thirty‐six resistance‐trained females and males were randomly assigned to the CS or the TS group.
Erik Hobein, Fabian Miltner, Ivan Jukic, Alexander Ferrauti, Thimo Wiewelhove   +4 more
wiley   +1 more source

Myofibrillar protein accumulation but reduced protein synthesis in PDCD4-depleted myotubes. [PDF]

PLoS One
Mora S, Alihemmat L, Davari LD, Ataie T, Mehranjani PN, Flewwelling L, Cheng AJ, Adegoke OAJ.   +7 more
europepmc   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, Volume 158, Issue 7, Page 1927-1940, 1 April 2026.
What's new? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

FBXO2-mediated KPTN ubiquitination promotes amino acid-dependent mTORC1 signaling and tumor growth. [PDF]

J Clin Invest
Gao J, Qing J, Li X, Luo Y, Huang L, Li H, Zhang H, Zhang J, Xiao P, Li J, Li T, He S.   +11 more
europepmc   +1 more source

A Systematic Review and User Reference of Phenotypic and Molecular Characteristics of Dexamethasone‐Mediated C2C12 Muscle Atrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Skeletal muscle is a vital part of human physiology and is responsible for numerous essential functions. Not surprisingly, the loss of skeletal muscle mass and function is common in several pathologies including atrophy and sarcopenia, which profoundly impact quality of life of those afflicted.
Alexa J. Klein, Roger A. Vaughan
wiley   +1 more source

Molecular mechanisms underlying the lifespan and healthspan benefits of dietary restriction across species. [PDF]

Front Genet
Fan J, Xu Y.
europepmc   +1 more source

Inhibition of N‐Terminal Acetyltransferase C Mitigates Endoplasmic Reticulum Stress–Mediated Muscle Atrophy in Cancer Cachexia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cancer cachexia is a complex syndrome marked by weight loss and muscle wasting, significantly impacting patient quality of life and survival. Mechanistically, it is characterized by suppressed protein synthesis and enhanced muscle catabolism, with the role of endoplasmic reticulum (ER) stress and unfolded protein response (UPR ...
Yusaku Kaneko, Tomohiro Hino, Shunta Taminishi, Yayoi Matoba, Daisuke Motooka, Atsushi Hoshino, Satoaki Matoba   +6 more
wiley   +1 more source

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.

Elife
Carroll B, Maetzel D, Maddocks ODK, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI.   +12 more
europepmc   +1 more source

MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis. [PDF]

Nat Commun
Gui W, Paral P, Dhamija B, Hagag E, Dusa M, Humajova J, Francova PV, Kucka J, Pankrac J, Schütz C, Armenis V, Ferrucci F, Schubert M, Guan K, Baenke F, Stange DE, Lehmann LH, Weckwerth W, Mirtschink P, Traikov S, Giuseppe B, Miracco C, Bornhäuser M, Minucci S, Sefc L, Macurek L, Elgendy M.   +26 more
europepmc   +1 more source

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos, Jeane Martinha dos Anjos Cordeiro, Luciano Cardoso Santos, Cleisla Souza Oliveira, Maria Clara Pascoal Santos Alvarez, Natália Panhoca Rodrigues, Jorge Lopez‐Tello, Amanda N. Sferruzzi‐Perri, Rogéria Serakides, Juneo Freitas Silva   +9 more
wiley   +1 more source