Results 61 to 70 of about 10,766 (255)

Latent Mycobacterium tuberculosis Infection Is Associated With a Higher Frequency of Mucosal-Associated Invariant T and Invariant Natural Killer T Cells

Frontiers in Immunology, 2018
Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to Mycobacterium tuberculosis (Mtb) being a major cause of death globally.
Dominic Paquin-Proulx, Priscilla R. Costa, Cassia G. Terrassani Silveira, Mariana P. Marmorato, Natalia B. Cerqueira, Matthew S. Sutton, Shelby L. O’Connor, Karina I. Carvalho, Douglas F. Nixon, Esper G. Kallas   +9 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

MAIT Cells in Barrier Tissues: Lessons from Immediate Neighbors

Frontiers in Immunology, 2020
Mucosal-associated invariant T (MAIT) cells are innate-like T cells present at considerable frequencies in human blood and barrier tissues, armed with an expanding array of effector functions in response to homeostatic perturbations.
Ali Amini, Ali Amini, Declan Pang, Carl-Philipp Hackstein, Carl-Philipp Hackstein, Paul Klenerman, Paul Klenerman   +6 more
doaj   +1 more source

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

Nature Communications, 2021
Mucosal-Associated Invariant T (MAIT) cells are associated with established functions during bacterial infection. Here the authors show inoculation with Francisella tularensis results in induction of MAIT cells associated with prototypic Th1 immunity and
Zhe Zhao, Huimeng Wang, Mai Shi, Tianyuan Zhu, Troi Pediongco, Xin Yi Lim, Bronwyn S. Meehan, Adam G. Nelson, David P. Fairlie, Jeffrey Y. W. Mak, Sidonia B. G. Eckle, Marcela de Lima Moreira, Carolin Tumpach, Michael Bramhall, Cameron G. Williams, Hyun Jae Lee, Ashraful Haque, Maximilien Evrard, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett, Zhenjun Chen   +21 more
doaj   +1 more source

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity [PDF]

, 2020
International audienceObesity is associated with low-grade chronic inflammation promoting insulin-resistance and diabetes. Gut microbiota dysbiosis is a consequence as well as a driver of obesity and diabetes.
Maguin, E, Lesnik, P, Lesnik, Philippe, da Silva, J, Lehuen, A, Maguin, Emmanuelle, Simoni, Yannick, Toubal, A, Cagninacci, L, Simoni, Y, Agnès Lehuen, Rhimi, M, Blandine Fruchet, Jennifer da Silva, Amine Toubal, da Silva, Jennifer, Corbett, AJ, Lantz, O, Yannick Simoni, Corbett, Alexandra, J, Kiaf, Badr, McCluskey, J, Beaudoin, Lucie, Fruchet, Blandine, Badr Kiaf, Corbett, Alexandra, Toubal, Amine, Alexandra J. Corbett, Cagninacci, Lucie, Olivier Lantz, Lucie Cagninacci, Rossjohn, J, Moez Rhimi, Jamie Rossjohn, Rhimi, Moez, Corbett, Alexandra J., Lantz, Olivier, Beaudoin, L, Fruchet, B, Kiaf, B, Mccluskey, James, Philippe Lesnik, Emmanuelle Maguin, Rossjohn, Jamie, Lehuen, Agnès, Lucie Beaudoin, James McCluskey   +46 more
core   +1 more source

Mucosal Associated Invariant T Cells in Cancer-Friend or Foe? [PDF]

, 2021
Mucosal associated invariant T (MAIT) cells are a population of unconventional T cells which can bridge the innate and adaptive immune systems. Well-described roles for MAIT cells include host protection against invading bacteria, fungi and viruses ...
Hogan, Andrew E., O’Neill, Chloe, Chloe O’Neill, Andrew E. Hogan, Cassidy, Féaron C., Féaron C. Cassidy, O’Shea, Donal, Donal O’Shea   +7 more
core   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Bacteria, mucosal‐associated invariant T cells and MR1 [PDF]

Immunology & Cell Biology, 2010
Certain subpopulations of T lymphoctyes show innate-like properties that distinguish them from conventional T cells and thus have been collectively termed innate T cells. Two extensively studied subsets of innate T cells implicated in pathogen detection are invariant natural killer T (iNKT) cells and γδ T cells. Conventional T cells detect pathogens in
Wei‐Jen Chua, Ted H Hansen
openaire   +1 more source

Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function [PDF]

, 2019
In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two ...
Ahlmanner, Filip
core