Results 141 to 150 of about 71,509 (231)

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang   +28 more
wiley   +1 more source

Protease‐Activated Receptor 2 Activation Provokes an Increase in Intracellular Calcium and Serotonin Secretion in a Human Enteroendocrine Cell Line

open access: yesCell Biochemistry and Function, Volume 43, Issue 11, November 2025.
ABSTRACT The P‐STS human ileal enteroendocrine tumor cell line responds with an increase in intracellular calcium and serotonin secretion to acetylcholine and histamine. Here we show that the cells react similarly to the protease‐activated receptor 2 (PAR2) agonists trypsin and SLIGRL‐NH2 peptide.
Beatrix Pfanzagl, Erika Jensen‐Jarolim
wiley   +1 more source

Autoantibodies Enhance Agonist Action and Binding to Cardiac Muscarinic Receptors in Chronic Chagas' Disease

open access: green, 2008
Ciria C. Hernández   +7 more
openalex   +1 more source

Adult Striatal Neurogenesis—A Comparative Approach Between Pigeons, Mice, Macaques, and Human

open access: yesJournal of Comparative Neurology, Volume 533, Issue 11, November 2025.
Striatal adult neurogenesis is an understudied field. Here, we add new quantitative data showing that pigeons provide high levels of adult neurogenesis in the striatum compared to mice. Besides, we show that macaque and human differ in their potential to produce adult‐born neurons at least in the caudate nucleus.
Christina Herold   +5 more
wiley   +1 more source

Nicotinic Acetylcholine Receptor Pathways in Cancer: From Psychiatric Clues to Therapeutic Opportunities

open access: yesCancer Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background The prevalence of cancer poses significant challenges to treatment, largely because of drug resistance along with other side effects. Current studies have been investigating the growth factors more than other biologic tumor features, such as neurobiologic features.
Mohammad Hossein Azadi   +3 more
wiley   +1 more source

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