Results 21 to 30 of about 6,378,630 (248)
Nanotechnology Applied to Stem Cell-Substratum Interactions [PDF]
, 2008 The modulation of biological interaction with artificial surfaces is a vital aspect of biomaterials research. Perhaps the most challenging area is transplantation involving the introduction of stem cells into the body with their ability to ...
Aref, Amirreza
core +7 more sources
Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA
Nature Communications, 2020 Alphaviruses need to selectively package genomic viral RNA for transmission, but the packaging mechanism remains unclear. Here, Brown et al. combine PAR-CLIP with biotinylated capsid protein (Cp) retrieval and identify multiple Cp binding sites on ...
Rebecca S. Brown +3 more
doaj +1 more source
Stem Cells International, 2021 The Pax7+ muscle stem cells (MuSCs) are essential for skeletal muscle homeostasis and muscle regeneration upon injury, while the molecular mechanisms underlying muscle stem cell fate determination and muscle regeneration are still not fully understood ...
Yu Liang +7 more
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Muscle stem cell adaptations to cellular and environmental stress
Skeletal Muscle, 2022 Background Lifelong regeneration of the skeletal muscle is dependent on a rare population of resident skeletal muscle stem cells, also named ‘satellite cells’ for their anatomical position on the outside of the myofibre and underneath the basal lamina ...
Maria Vittoria Gugliuzza, Colin Crist
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Methods for Accurate Assessment of Myofiber Maturity During Skeletal Muscle Regeneration
Frontiers in Cell and Developmental Biology, 2020 Adult skeletal muscle has a remarkable ability to regenerate. Regeneration of mature muscle fibers is dependent on muscle stem cells called satellite cells.
Yuki Yoshimoto +4 more
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Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells [PDF]
, 2015 © 2015 Macmillan Publishers Limited. All rights reserved. microRNA-34a (miR-34a) and sirtuin 1 (SirT1) have been extensively studied in tumour biology and longevityaging, but little is known about their functional roles in smooth muscle cell (SMC ...
L A Luong +35 more
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Epigenetic regulation of satellite cell fate during skeletal muscle regeneration
Skeletal Muscle, 2021 In response to muscle injury, muscle stem cells integrate environmental cues in the damaged tissue to mediate regeneration. These environmental cues are tightly regulated to ensure expansion of muscle stem cell population to repair the damaged myofibers ...
Jimmy Massenet +3 more
doaj +1 more source
MicroRNAs play a role in human embryonic stem cell differentiation into endothelial cells [PDF]
, 2011 PhDThe past recent years have seen a surge of evidence demonstrating the regulation of microRNAs (miRNAs) in a myriad of vascular biology events such as cardiogenesis.
Luo, Zhenling
core +4 more sources
NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration
Biological Research, 2023 Background Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, including the ubiquitin ...
Felipe Cabezas +6 more
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BMC Musculoskeletal Disorders, 2017 Background Transplanting myogenic cells and scaffolds for tissue engineering in skeletal muscle have shown inconsistent results. One of the limiting factors is neovascularization at the recipient site.
Lise K. Hansen +5 more
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