Results 1 to 10 of about 126,969 (246)
Zika virus infection differentially affects genome-wide transcription in neuronal cells and myeloid dendritic cells. [PDF]
PLoS ONE, 2020 Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has attracted global attention and international awareness. ZIKV infection exhibits mild symptoms including fever and pains; however, ZIKV has recently been shown to be related to increased ...
Tamina Park +4 more
doaj +2 more sources
Negative impact of proteinuria on circulating myeloid dendritic cells. [PDF]
Clin Exp Nephrol, 2019 A decrease in absolute numbers (abs.) of circulating dendritic cells (DCs) and recruitment into target organs has been reported, but whether the level of proteinuria associates with circulating DC abs. has not been clarified.We conducted a cross-sectional study of 210 patients with kidney disease aged 21-96 years who were admitted to our hospital for ...
Ikeda M +10 more
europepmc +4 more sources
Myeloid Dendritic Cells Induce HIV Latency in Proliferating CD4+ T Cells. [PDF]
J Immunol, 2018 Abstract HIV latency occurs predominantly in long-lived resting CD4+ T cells; however, latent infection also occurs in T cell subsets, including proliferating CD4+ T cells. We compared the establishment and maintenance of latent infection in nonproliferating and proliferating human CD4+ T cells cocultured with syngeneic myeloid dendritic
Kumar NA +6 more
europepmc +4 more sources
Biology, 2023 Mesenchymal Stromal Cells (MSCs) derived from bone marrow are widely tested in clinical trials as a cellular therapy for potential inflammatory disorders. The mechanism of action of MSCs in mediating immune modulation is of wide interest.
Crystal C. Uwazie +6 more
doaj +1 more source
Dendritic Cell-Based Immunotherapy for Myeloid Leukemias [PDF]
Frontiers in Immunology, 2013 Acute and chronic myeloid leukemia (AML, CML) are hematologic malignancies arising from oncogene-transformed hematopoietic stem/progenitor cells known as leukemia stem cells (LSCs). LSCs are selectively resistant to various forms of therapy including irradiation or cytotoxic drugs.
Christian Martijn Schürch +4 more
openaire +4 more sources
Dendritic cell ontogeny: A human dendritic cell lineage of myeloid origin [PDF]
Proceedings of the National Academy of Sciences, 1997 Dendritic cells (DC) have been thought to represent a family of closely related cells with similar functions and developmental pathways. The best-characterized precursors are the epidermal Langerhans cells, which migrate to lymphoid organs and become activated DC in response to inflammatory stimuli. Here, we demonstrate that a large subset of DC in the
J, Olweus +6 more
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Oral chronic graft-versus-host disease: analysis of dendritic cells subpopulations [PDF]
Anais Brasileiros de Dermatologia, 2014 The graft-versus-host disease is the major cause of morbidity and mortality in patients who have undergone hematopoietic stem cell transplantation. Aiming at contributing to the understanding of the role of myeloid and plasmacytoid dendritic cells, and ...
Clara Marino Espricigo Botari +4 more
doaj +2 more sources
Myeloid dendritic cells in HIV-1 infection [PDF]
Current Opinion in HIV and AIDS, 2011 Myeloid dendritic cells (mDCs) are pivotal players in HIV-1 infection. They promote transmission and spread and at the same time are critical for recognizing HIV-1 and initiating immune responses to fight infection. Notably, their immunostimulatory capabilities can be harnessed to design better HIV-1 vaccines. In this review, advances in these areas of
Nina, Derby +2 more
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Increased Blood Myeloid Dendritic Cells and Dendritic Cell-Poietins in Langerhans Cell Histiocytosis [PDF]
The Journal of Immunology, 2005 Abstract Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, is a reactive proliferative disease of unknown pathogenesis. Current therapies are based on nonspecific immunosuppression. Because multiple APCs, including Langerhans cells and macrophages, are involved in the lesion formation, we surmised that LCH is a ...
Alexandre, Rolland +6 more
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Dendritic Cell-Based Immunotherapy of Acute Myeloid Leukemia [PDF]
Journal of Clinical Medicine, 2019 Acute myeloid leukemia (AML) is a type of blood cancer characterized by the uncontrolled clonal proliferation of myeloid hematopoietic progenitor cells in the bone marrow. The outcome of AML is poor, with five-year overall survival rates of less than 10% for the predominant group of patients older than 65 years.
Heleen H. Van Acker +9 more
openaire +3 more sources