Results 31 to 40 of about 126,969 (246)

Isolation of Myeloid Dendritic Cells and Epithelial Cells from Human Thymus [PDF]

Journal of Visualized Experiments, 2013
In this protocol we provide a method to isolate dendritic cells (DC) and epithelial cells (TEC) from the human thymus. DC and TEC are the major antigen presenting cell (APC) types found in a normal thymus and it is well established that they play distinct roles during thymic selection.
Stoeckle, Christina, Rota, Ioanna A., Tolosa, Eva, Haller, Christoph, Melms, Arthur, Adamopoulou, Eleni   +5 more
openaire   +3 more sources

Plasmacytoid Dendritic Cell Infiltration in Acute Myeloid Leukemia.

Cancer management and research, 2020
Increasing evidence has demonstrated that plasmacytoid dendritic cells (PDCs) in the tumor microenvironment (TME) play an important role in tumorigenesis and progression. PDC infiltration has been found in certain malignancies such as classic Hodgkin's lymphoma and chronic myelomonocytic leukemia.
Zhu,Lidan, Wang,Ping, Zhang,Wei, Li,Qiong, Xiong,Jingkang, Li,Jiali, Deng,Xiaojuan, Liu,Yao, Yang,Chao, Kong,Peiyan, Peng,Xiangui, Zhong,Jiang F, Rao,Jun, Zhang,Xi   +13 more
openaire   +4 more sources

DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells [PDF]

The Journal of Immunology, 2014
Abstract Many members of the DEXD/H box helicase family play important roles in the innate immune system against viral infection. Therefore, we isolated dsRNA complex in myeloid dendritic cells. We found that DHx15, a DEXDc helicase family member, is one of the components of this complex.
Hongbo, Lu, Ning, Lu, Leiyun, Weng, Bin, Yuan, Yong-Jun, Liu, Zhiqiang, Zhang   +5 more
openaire   +2 more sources

Distribution of Myeloid and Plasmacytoid Dendritic Cell Subpopulations in Peripheral Blood of Hyperprolactinemic Women

Iranian Journal of Allergy, Asthma and Immunology, 2021
Dendritic cells (DCs) play key roles in regulating the immune response using the specialized function of processing and presenting antigens. Prolactin (PRL), a hormone produced by the pituitary gland, participates in DC maturation and function.
Fatemeh Raeesi Nejad, Mohammad Mahdi Mohammadi, Mojgan Sanjari, Reza Malkpour Afshar, Elham Jafari   +4 more
doaj   +1 more source

Platelet concentrates modulate myeloid dendritic cell immune responses

Platelets, 2017
Platelet transfusion has been reported to modulate the recipients' immune system. To date, the precise mechanism(s) driving poor patient outcomes (e.g., increased rate of mortality, morbidity, infectious complications and prolonged hospital stays) following platelet transfusion are largely undefined. To determine the potential for platelet concentrates
Katrina K. Ki, Helen M. Faddy, Robert L. Flower, Melinda M. Dean   +3 more
openaire   +4 more sources

Restricted Access to Myeloid Cells Explained

Viruses, 2011
The lentiviral accessory protein, Vpx, is known to counteract a restriction factor that is specific to myeloid cells, such as macrophages and dendritic cells. This review summarizes the findings in two seminal studies that identify SAMHD1 as the cellular
Vicente Planelles
doaj   +1 more source

Blood myeloid cells differentiate to lung resident cells and respond to pathogen stimuli in a 3D human tissue-engineered lung model

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Respiratory infections remain a leading global health concern. Models that recapitulate the cellular complexity of the lower airway of humans will provide important information about how the immune response reflects the interactions between
Mandi M. Roe, Taylor Do, Sean Turner, Allison M. Jevitt, Magdalena Chlebicz, Karley White, Antonius G. P. Oomens, Susannah Rankin, Susan Kovats, Susan Kovats, Heather Gappa-Fahlenkamp   +10 more
doaj   +1 more source

Myeloid dendritic cells in inclusion‐body myositis and polymyositis [PDF]

Muscle & Nerve, 2006
AbstractDendritic cells (DCs), immune system cells central to the development of immunity, have not previously been reported in muscle in inclusion‐body myositis (IBM). We performed immunohistochemical studies on muscle biopsy specimens from 50 patients using monoclonal antibodies that distinguish two classes of DCs, myeloid DC and plasmacytoid DC.
Steven A, Greenberg, Geraldine S, Pinkus, Anthony A, Amato, Jack L, Pinkus   +3 more
openaire   +2 more sources

The role of DC-SIGN as a trans-receptor in infection by MERS-CoV

Frontiers in Cellular and Infection Microbiology, 2023
DC-SIGN is a C-type lectin expressed in myeloid cells such as immature dendritic cells and macrophages. Through glycan recognition in viral envelope glycoproteins, DC-SIGN has been shown to act as a receptor for a number of viral agents such as HIV ...
Nuria Labiod, Joanna Luczkowiak, María M. Tapia, Fátima Lasala, Rafael Delgado, Rafael Delgado, Rafael Delgado   +6 more
doaj   +1 more source

Exploration of the Causal Roles of Immune Cells and Inflammatory Proteins in Aortic Dissection via Mendelian Randomization

Cardiovascular Innovations and Applications
Aortic dissection is a life-threatening condition with complex immunological underpinnings. This study was aimed at exploring the causal relationships among immune cells, inflammatory proteins, and aortic dissection, through Mendelian randomization ...
Yueye Chen, Ye Chen, Jingyu Zhu, Jamol Uzokov, Yuemeng Li, Jingming Feng, Ayumi Aurea Miyakawa, Kun Liu, Yanshuo Han   +8 more
doaj   +1 more source