Results 31 to 40 of about 32,334 (225)
Specific Activation of the Acetylcholine Receptor Subunit Genes by MyoD Family Proteins [PDF]
Journal of Biological Chemistry, 2003 Whether the myogenic regulatory factors (MRFs) of the MyoD family can discriminate among the muscle gene targets for the proper and reproducible formation of skeletal muscle is a recurrent question. We have previously shown that, in Xenopus laevis, myogenin specifically transactivated muscle structural genes in vivo.
Frédéric, Charbonnier +6 more
openaire +2 more sources
Targeting PKCθ promotes satellite cell self-renewal [PDF]
, 2020 Skeletal muscle regeneration following injury depends on the ability of satellite cells (SCs) to proliferate, self-renew, and eventually differentiate. The factors that regulate the process of self-renewal are poorly understood. In this study we examined
Benedetti, Anna +4 more
core +1 more source
Developing cardiac and skeletal muscle share fast-skeletal myosin heavy chain and cardiac troponin-I expression [PDF]
, 2012 Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial ...
A Du +39 more
core +12 more sources
Data on MyoD reduction by autophagy in C2C12 cells
Data in Brief, 2017 Autophagy is a highly regulated physiologic mechanism in which cells maintain homeostasis by degrading excessive or unnecessary proteins and damaged or aged organelles through the lysosomal machinery (Yorimitsu and Klionsky, 2005) [1].
Yeong-Min Yoo, Yung Chul Park
doaj +1 more source
Applied Sciences, 2023 Sarcopenia is an aging-related disease that involves the gradual loss of muscle mass and function. However, no suitable therapeutic drugs are currently available. Accordingly, the purpose of the present study was to evaluate the effectiveness of rosemary
Jun Ho Lee +6 more
doaj +1 more source
The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]
, 2015 Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Anna eNoble +9 more
core +2 more sources
Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]
, 2019 Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John +2 more
core +1 more source
Frontiers in Physiology, 2020 Muscle satellite cells (MSCs) are myogenic stem cells that play a critical role in post-hatch skeletal muscle growth and regeneration. Activation of regeneration pathways to repair muscle fiber damage requires both the proliferation and differentiation ...
Tamara Z. Ferreira +7 more
doaj +1 more source
MYOD induced lnc-MEG3 promotes porcine satellite cell differentiation via interacting with DLST
Epigenetics, 2023 Long non-coding RNAs (lncRNAs) are involved in the process of muscle cell differentiation and play an important role. Previous studies have shown that lncRNA-MEG3 promotes the differentiation of porcine skeletal muscle satellite cells (PSCs), but the ...
Quan Liu +7 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2023 E3 ubiquitin ligases are closely related to cell division, differentiation, and survival in all eukaryotes and play crucial regulatory roles in multiple biological processes and diseases. While Deltex2, as a member of the DELTEX family ubiquitin ligases,
Zhu Qi +7 more
doaj +1 more source