Results 21 to 30 of about 32,334 (225)
Journal of Developmental Biology, 2023 The MyoD gene was duplicated during the teleost whole genome duplication and, while a second MyoD gene (MyoD2) was subsequently lost from the genomes of some lineages (including zebrafish), many fish lineages (including Alcolapia species) have retained ...
Lewis J. White +4 more
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iScience, 2021 Summary: While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation of fibroblasts to myoblasts promotes
Lavinia Bisceglie +11 more
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Differential Cooperation between Heterochromatin Protein HP1 Isoforms and MyoD in Myoblasts [PDF]
Journal of Biological Chemistry, 2008 Mechanisms of transcriptional repression are important during cell differentiation. Mammalian heterochromatin protein 1 isoforms HP1alpha, HP1beta, and HP1gamma play important roles in the regulation of chromatin structure and function. We explored the possibility of different roles for the three HP1 isoforms in an integrated system, skeletal muscle ...
Yahi, Hakima +9 more
openaire +3 more sources
Applied Sciences, 2022 Direct reprogramming of somatic cells to myoblasts and myotubes holds great potential for muscle development, disease modeling and regenerative medicine.
Boram Son +6 more
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Direct Reprogramming of Fibroblasts to Myocytes via Bacterial Injection of MyoD Protein [PDF]
Cellular Reprogramming, 2013 Forced exogenous gene expression has been well characterized as an effective method for directing both cellular differentiation and dedifferentiation. However, transgene expression is not amenable for therapeutic application due to potential insertional mutagenesis.
Candace, Bichsel +6 more
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Growth factors improve the proliferation of Jeju black pig muscle cells by regulating myogenic differentiation 1 and growth-related genes [PDF]
Animal Bioscience, 2021 Objective The growth rate of pigs is related to differentiation and proliferation of muscle cells, which are regulated by growth factors and expression of growth-related genes. Thus, the objective of this study was to establish optimal culture conditions
Jinryong Park +8 more
doaj +1 more source
Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia [PDF]
, 2020 Background: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer-associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy
Chiappalupi, S. +9 more
core +1 more source
Mos Activates Myogenic Differentiation by Promoting Heterodimerization of MyoD and E12 Proteins [PDF]
Molecular and Cellular Biology, 1997 The activities of myogenic basic helix-loop-helix (bHLH) factors are regulated by a number of different positive and negative signals. Extensive information has been published about the molecular mechanisms that interfere with the process of myogenic differentiation, but little is known about the positive signals.
J L, Lenormand +5 more
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International Brazilian Journal of Urology, 2015 Purpose:RNA activation (RNAa) is a mechanism of gene activation triggered by promoter-targeted small double stranded RNAs (dsRNAs), also known as small activating RNAs (saRNAs).
Chenghe Wang +10 more
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Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. [PDF]
, 2015 Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population.
Blackshear, Perry J +7 more
core +2 more sources