Results 1 to 10 of about 32,252 (159)

CHAMP1 is an essential regulator for human myoblast fusion and muscle development [PDF]

Nature Communications
Human skeletal muscle comprises myofibers formed by fusion of thousands of myoblasts. This process depends on tightly regulated, muscle-specific fusogens, but its genetic control remains poorly understood.
Haifeng Zhang, Min Zhou, Zheng Zhang, Zhaoning Wang, Ruifeng Shi, Yushu Wang, Xiaolin Wei, Renjie Shang, Jianwen Li, Cuiyu He, Jin Xie, Yarui Diao, Pengpeng Bi   +12 more
doaj   +2 more sources

Skipjack tuna bone derived biocalcium ameliorates C2C12 myotube atrophy through microRNA29b regulation [PDF]

Scientific Reports
We investigated the protective effects of skipjack tuna (Katsuwonus pelamis) bone-derived biocalcium (Bio) against dexamethasone-induced atrophy in C2C12 myotubes. Bio rescued atrophic morphology, increasing myotube diameter dose-dependently.
Sompot Jantarawong, Theeraphol Senphan, Chanokwanan Youngruk, Nicha Thongchai, Papitchaya Watcharanurak, Pasjan Satrimafitrah, Yuya Yamaguchi, Kazuya Hasegawa, Yutthana Pengjam   +8 more
doaj   +2 more sources

Nandrolone-induced nuclear accumulation of MyoD protein is mediated by Numb, a Notch inhibitor, in C2C12 myoblasts. [PDF]

Physiol Rep, 2018
Liu XH, De Gasperi R, Bauman WA, Cardozo CP.   +3 more
europepmc   +2 more sources

PAX7 and MyoD Proteins Expression in Response to Eccentric and Concentric Resistance Exercise in Active Young Men [PDF]

Cell Journal, 2023
Objective: Satellite cells play an important role in muscle regeneration, which this process can be affected by differentgenes including PAX7 and MyoD. Exercise training known as an important strategy for mediating the satellite cell’sfunction. Therefore,
Somayeh Karimi Majd, Mandana Gholami, Behzad Bazgir   +2 more
doaj   +1 more source

Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity

iScience, 2023
Summary: Myoblast determination protein 1 (MyoD) dynamics define the activation status of muscle stem cells (MuSCs), aiding in muscle tissue regeneration after injury.
Ryo Fujita, Seiya Mizuno, Taketaro Sadahiro, Takuto Hayashi, Takehito Sugasawa, Fumihiro Sugiyama, Yusuke Ono, Satoru Takahashi, Masaki Ieda   +8 more
doaj   +1 more source

Stress-induced C/EBP homology protein (CHOP) represses MyoD transcription to delay myoblast differentiation. [PDF]

PLoS ONE, 2011
When mouse myoblasts or satellite cells differentiate in culture, the expression of myogenic regulatory factor, MyoD, is downregulated in a subset of cells that do not differentiate.
Joel Alter, Eyal Bengal
doaj   +1 more source

Discovery of Novel Stimulators of Pax7 and/or MyoD: Enhancing the Efficacy of Cultured Meat Production through Culture Media Enrichment

Biosensors, 2023
The principles of myogenesis play crucial roles in the production of cultured meat, and identifying protein stimulators associated with myogenesis holds great potential to enhance the efficiency of this process.
In-Sun Yu, Yae Rim Choi, Jungseok Choi, Mina K. Kim, Chang Hwa Jung, Min Young Um, Min Jung Kim   +6 more
doaj   +1 more source

MyoD is a 3D genome structure organizer for muscle cell identity

Nature Communications, 2022
Pioneer transcription factors (TFs) have been proposed to act as protein anchors to orchestrate cell type-specific 3D genome architecture. MyoD is a pioneer TF for myogenic lineage specification.
Ruiting Wang, Fengling Chen, Qian Chen, Xin Wan, Minglei Shi, Antony K. Chen, Zhao Ma, Guohong Li, Min Wang, Yachen Ying, Qinyao Liu, Hu Li, Xu Zhang, Jinbiao Ma, Jiayun Zhong, Meihong Chen, Michael Q. Zhang, Yong Zhang, Yang Chen, Dahai Zhu   +19 more
doaj   +1 more source

Epigenetic reprogramming of muscle progenitors: inspiration for clinical therapies [PDF]

, 2015
In the context of regenerative medicine, based on the potential of stem cells to restore diseased tissues, epigenetics is becoming a pivotal area of interest.
Consalvi, Silvia, Saccone, Valentina, Sandona', Martina   +2 more
core   +17 more sources

The core binding factor CBF negatively regulates skeletal muscle terminal differentiation. [PDF]

PLoS ONE, 2010
BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits, Runx1/AML-1 and CBF beta or CBFbeta. CBF was originally described as a regulator of hematopoiesis.
Ophélie Philipot, Véronique Joliot, Ouardia Ait-Mohamed, Céline Pellentz, Philippe Robin, Lauriane Fritsch, Slimane Ait-Si-Ali   +6 more
doaj   +1 more source