Results 161 to 170 of about 1,662 (193)

Effect of Tongue Exercise on Improving Age‐Related Decline in Swallowing Function: A Systematic Review and Meta‐Analysis of Animal Model–Based Interventions

Journal of Oral Rehabilitation, Volume 53, Issue 3, Page 807-818, March 2026.
ABSTRACT Background Age‐related decline in swallowing function (dysphagia) increases the risk of aspiration pneumonia and reduces quality of life in older adults. However, the efficacy of swallowing‐targeted interventions in aging remains unclear. Objective This study aimed to systematically review the interventions for age‐related dysphagia in aged ...
Han‐Na Kim, Ji‐Youn Kim
wiley   +1 more source

Alternative Pathways of Acetylcholine Release in the Colon: Role of High‐Affinity Choline Transporters

Neurogastroenterology &Motility, Volume 38, Issue 3, March 2026.
Mechanisms of Acetylcholine release, including typical and atypical release under neuronal blockade. Left panel illustrates the classical (quantal) cholinergic transmission and the right panel the mechanism described in the present study. High‐Affinity Choline Transporter (HCT), Acetylcholine (ACh), Acetylcholinesterase (ACE), and Tetrodotoxin (TTX ...
A. Martinez‐Daunis, B. Yordanova, S. Traserra, P. Vergara, M. Jimenez   +4 more
wiley   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology, Volume 111, Issue 3, Page 1093-1108, 1 March 2026.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
wiley   +1 more source

Role of Septin7 in mitochondrial dynamics and oxidative metabolism in C2C12 skeletal muscle cells

The Journal of Physiology, Volume 604, Issue 5, Page 1971-1994, 1 March 2026.
Abstract figure legend Knockdown of Septin7 alters the expression of markers responsible for mitochondrial dynamics. Members of the electron transport chain are also affected by diminished Septin7 level resulting in functional changes of mitochondrial respiration. Abstract Mitochondria are dynamic organelles that undergo fusion and fission.
Andrea Telek, Ivett Gabriella Szabó, Anikó Keller‐Pintér, Mónika Gönczi, Eliza Guti, László Szabó, Brigitta Tillmann, Zoltán Márton Kohler, László Juhász, Péter Bai, Szilárd Póliska, Zsuzsanna Gaál, László Csernoch, János Fodor   +13 more
wiley   +1 more source

Functional expression of inwardly rectifying and ATP‐sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells

The Journal of Physiology, Volume 604, Issue 5, Page 1820-1839, 1 March 2026.
Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira, Daniel Morales‐Cano, Laura Moreno, Beatriz de Olaiz, Rui Adão, Angel Cogolludo, Francisco Perez‐Vizcaino, Maria Sancho   +7 more
wiley   +1 more source

Lactate supplementation modulates molecular and functional responses during chronic neuromuscular electrical stimulation in male rats

Physiological Reports, Volume 14, Issue 5, March 2026.
Abstract Lactate is increasingly recognized as a signaling molecule that modulates muscle plasticity. We examined the effects of oral L‐sodium lactate supplementation on skeletal muscle adaptation to chronic neuromuscular electrical stimulation (NMES) in rats.
Toshinori Yoshihara, Yasushi Koriyama, Sakura Ogawa, Hisashi Naito   +3 more
wiley   +1 more source

Senescent‐Like Myofibers Contribute to Anti‐Regenerative Cytokine Signaling in Duchenne Muscular Dystrophy

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
p16 expression in DMD model rats induces a senescent‐like state in myofibers accompanied by p16 and cytokine gene expression, reshaping systemic humoral environments. This cytokine‐rich milieu suppresses skeletal muscle regeneration, as demonstrated by impaired regeneration of transplanted wild‐type muscle.
Masanari Ikeda, Yukie Tanaka, Hidetoshi Sugihara, Takashi Matsuwaki, Keitaro Yamanouchi   +4 more
wiley   +1 more source

CD47 Promotes, While Exposure to Apoptotic Cells Destroys the Fusion Program of Differentiating Myoblasts

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
(A) CD47, acting in a cis‐manner with integrins, promotes myoblast fusion. TSP‐1 serves as a bridging molecule for these proteins to recognize PS on the surface of the other fusing myoblasts. (B) Blocking of these signals by neutralizing antibodies reduces cell fusion. Inhibition of PIEZO1 activity by constantly expressed PS on apoptotic cells leads to
Maysaa Adil Ali, Albert Bálint Papp, Éva Garabuczi, Áron Károly Gere, Beatrix Dienes, Mónika Gönczi, György Vámosi, Krisztina Köröskényi, László Csernoch, Zsuzsa Szondy, Zsolt Sarang   +10 more
wiley   +1 more source

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Immunofluorescence analysis of myogenic differentiation

2022
Skeletal muscle is a highly regenerative tissue that can efficiently recover from various damages caused by injuries and excessive exercises. In adult muscle, stem cells termed satellite cells are mitotically quiescent but activated upon muscle damages to enter the cell cycle as myogenic precursor cells or myoblasts. After several rounds of cell cycles,
Atsushi, Asakura, Nobuaki, Kikyo
openaire   +2 more sources

Hormones, Growth Factors, and Myogenic Differentiation

Annual Review of Physiology, 1991
Three families of growth factors/hormones have major effects on the differentiation of skeletal muscle cells. Two (FGF and TGF-beta) are potent inhibitors, and the third (IGF) exhibits a biphasic stimulatory action (but is not inhibitory even at high concentrations).
J R, Florini, D Z, Ewton, K A, Magri
openaire   +3 more sources