Results 31 to 40 of about 1,662 (193)
PFN1 Inhibits Myogenesis of Bovine Myoblast Cells via Cdc42-PAK/JNK
Cells, 2022 Myoblast differentiation is essential for the formation of skeletal muscle myofibers. Profilin1 (Pfn1) has been identified as an actin-associated protein, and has been shown to be critically important to cellular function.
Jingjing Zi +10 more
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Stem Cell Research, 2018 Adult skeletal muscle regeneration relies on the activity of satellite cells residing in the skeletal muscle niche. However, systemic and intrinsic factors decrease the myogenic differentiation potential of satellite cells thereby impairing muscle ...
Aref Shahini +5 more
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Scientific Reports, 2017 Myogenic differentiation results in different cell type cooperation, but the molecules involved in the myogenic cell activation remain elusive. Here, we show that muscle-resident pre-adipocytes promote myogenic differentiation through the secretion of ...
Thierry Rouaud +6 more
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Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome
Advanced Science, 2021 Obesity during pregnancy leads to adverse health outcomes in offspring. However, the initial effects of maternal obesity (MO) on embryonic organogenesis have yet to be thoroughly examined.
Liang Zhao +8 more
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Cells, 2023 Skeletal myogenesis is an intricate process involving the differentiation of progenitor cells into myofibers, which is regulated by actin cytoskeletal dynamics and myogenic transcription factors.
Mai Thi Nguyen +3 more
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Physiological Reports, 2023 TRPM8 agonist has been reported to promote osteogenic differentiation of mesenchymal stem cells (MSCs), therefore we evaluated whether cooling‐induced activation of TRPM8 promotes myogenic differentiation of MSCs.
Ryo Takagi +5 more
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Role of MiR-325-3p in the Regulation of CFL2 and Myogenic Differentiation of C2C12 Myoblasts
Cells, 2021 Skeletal myogenesis is required to maintain muscle mass and integrity, and impaired myogenesis is causally linked to the etiology of muscle wasting. Recently, it was shown that excessive uptake of saturated fatty acids (SFA) plays a significant role in ...
Mai Thi Nguyen, Wan Lee
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Molecular mechanisms regulating myogenic determination and differentiation [PDF]
Frontiers in Bioscience, 2000 The myogenic regulatory factors are necessary for the determination and terminal differentiation of skeletal muscle. Gene targeting experiments have demonstrated that MyoD and Myf5 are important for myogenic determination whereas myogenin and MRF4 are important for terminal differentiation and lineage maintenance. During development, all trunk skeletal
R L, Perry, M A, Rudnick
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BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis
Scientific Reports, 2017 Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure.
Thomas C. Roberts +7 more
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Inhibition of glycogen synthase kinase-3β attenuates glucocorticoid-induced suppression of myogenic differentiation in vitro. [PDF]
PLoS ONE, 2014 Glucocorticoids are the only therapy that has been demonstrated to alter the progress of Duchenne muscular dystrophy (DMD), the most common muscular dystrophy in children.
Zhenyu Ma +4 more
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