Results 91 to 100 of about 4,176 (133)

N1-Methyladenosine-Related lncRNAs Are Potential Biomarkers for Predicting Prognosis and Immune Response in Uterine Corpus Endometrial Carcinoma. [PDF]

Oxid Med Cell Longev, 2022
Liu J, Geng R, Zhong Z, Zhang Y, Ni S, Liu W, Du M, Bai J.   +7 more
europepmc   +1 more source

N1-Methyladenosine (m1A) Regulation Associated With the Pathogenesis of Abdominal Aortic Aneurysm Through YTHDF3 Modulating Macrophage Polarization. [PDF]

Front Cardiovasc Med, 2022
Wu Y, Jiang D, Zhang H, Yin F, Guo P, Zhang X, Bian C, Chen C, Li S, Yin Y, Böckler D, Zhang J, Han Y.   +12 more
europepmc   +1 more source

The role of RNA 2′-O-methylation in prostate cancer [PDF]

2′-O-methylation (Nm) represents a pervasive RNA modification occurring in multiple RNA species, including messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), microRNA (miRNA), and PIWI-interacting RNA (piRNA).
Wang, Rui, Wu, Siqi, yi, yang
core   +2 more sources

Investigation of Prokaryotic Non-coding RNS and Their Modifications [PDF]

Non-coding RNAs (ncRNA) are transcripts produced by the cell that are not translated into proteins yet play a fundamental role in maintaining proper regulation and function of cellular activities. The term encompasses a myriad of different types of RNAs,
Foo, Marcus Chun Hoe
core   +1 more source

ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through N1-methyladenosine modification of circCDK17. [PDF]

Acta Pharm Sin B, 2023
Zhang J, Li Y, Zhang J, Liu L, Chen Y, Yang X, Liao X, He M, Jia Z, Fan J, Bian JS, Nie X.   +11 more
europepmc   +1 more source

Emerging roles of RNA methylation modifications in environmental metalloid or metal pollutants toxicity

Ecotoxicology and Environmental Safety
The common environmental metalloid or metal pollutants such as arsenic, cadmium, chromium, lead, aluminum, cobalt and manganese have increasingly significant impacts on public health.
Rongxian Li, Yuan Zhao, Jiao Dai, Nan Zhang, Jiamin Yuan, De Liu, Zuoshun He, Jie Yang, Shiyan Gu   +8 more
doaj   +1 more source

N¹-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction. [PDF]

Cell Death Discov, 2023
Qi Z, Zhang C, Jian H, Hou M, Lou Y, Kang Y, Wang W, Lv Y, Shang S, Wang C, Li X, Feng S, Zhou H.   +12 more
europepmc   +1 more source

Unravelling the impact of RNA methylation genetic and epigenetic machinery in the treatment of cardiomyopathy

Pharmacological Research
Cardiomyopathy (CM) represents a heterogeneous group of diseases primarily affecting cardiac structure and function, with genetic and epigenetic dysregulation playing a pivotal role in its pathogenesis.
Li Liu, Linxing Yu, Yubo Wang, Liufang Zhou, Yan Liu, Xingshou Pan, Jianjun Huang   +6 more
doaj   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications
Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
doaj   +1 more source

N¹-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism. [PDF]

Nat Commun, 2021
Wang Y, Wang J, Li X, Xiong X, Wang J, Zhou Z, Zhu X, Gu Y, Dominissini D, He L, Tian Y, Yi C, Fan Z.   +12 more
europepmc   +1 more source