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Proceedings of the 28th ACM International Conference on Information and Knowledge Management, 2019 Textile pattern design is a challenging task that can be hardly resolved by a single deep neural network, due to the requirements on high resolution, periodic tiling, copyright protection and aesthetic preference of designers. In this paper, we present our NAD system which can automatically produce high-quality textile patterns for printing industry ...
Zhifei Pang +4 more
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Sarcopenia and Muscle Aging: A Brief Overview [PDF]
Endocrinology and Metabolism, 2020 The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns.
Tam Dao +8 more
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Recent developments and future perspectives in aging and macrophage immunometabolism
AIMS Molecular Science, 2021 Aging is the strongest contributor to the development and severity of many chronic and infectious diseases, primarily through age-related increases in low-grade inflammation (inflammaging) and decreases in immune function (immunosenescence).
Brandt D. Pence
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Сибирский научный медицинский журнал, 2021 The aim of the study was to assess the level of NAD+ in the brain of mice treated with beta-amyloid (Aβ), as well as to determine the activity of ADP-ribosyl cyclase/CD38 and the number of CD38-immunopositive neurons, astrocytes and endothelial cells ...
A. A. Semenova +4 more
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Вавиловский журнал генетики и селекции, 2017 Studies of the last decade reveal a new sight on the possible link between aging processes and circadian rhythm. New data on the role of the NAD+-dependent histone deacetylase SIRT1 in the integration of regulation pathways for circadian rhythms and ...
N. L. Podkolodnyy +2 more
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Biochemical Journal, 2004 NAD+ and its metabolites serve important functions in intracellular signalling. NAD+-mediated regulatory processes also take place on the cell surface, particularly of immune cells. In this issue of the Biochemical Journal, Gerth et al. have demonstrated a new mechanism of Ca2+ uptake into monocytes which is triggered by NAD+ or its degradation product,
Mathias, Ziegler, Marc, Niere
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Nicotinamide prevention in diabetes-induced alterations in the rat liver
Endocrine Regulations, 2023 Objective. The study was performed to elucidate whether nicotinamide (NAm) can attenuate the diabetes-induced liver damage by correction of ammonia detoxifying function and disbalance of NAD-dependent processes in diabetic rats.
Kuchmerovska Tamara +5 more
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Nicotinamide adenine dinucleotide (NAD+). Formal potential of the NAD+/NAD· couple and NAD· dimerization rate [PDF]
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1984 The rate constant, kd, for the dimerization of the free radical (NAD), produced on the initial one-electron reduction of NAD+, was measured by double potential-step chronoamperometry, fast-scan cyclic voltammetry (cathodic-anodic peak current ratio) and slow-scan cyclic voltammetry (peak potential shift) for a medium in which neither NAD+ nor its ...
M A, Jensen, P J, Elving
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Protective role of p53 in doxorubicin-induced cardiomyopathy as a mitochondrial disease
Molecular & Cellular Oncology, 2020 Doxorubicin is widely used against cancer but carries the risk of a progressive cardiomyopathy associated with mitochondrial loss. Using genetic models, our recent study demonstrates that mitochondrial genomic DNA regulation by tumor protein p53 (TP53 ...
Masahiro Nishi +2 more
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Hypothalamic NAD+-Sirtuin Axis: Function and Regulation
Biomolecules, 2020 The rapidly expanding elderly population and obesity endemic have become part of continuing global health care problems. The hypothalamus is a critical center for the homeostatic regulation of energy and glucose metabolism, circadian rhythm, and aging ...
Eun Roh, Min-Seon Kim
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