Investigation of sand in piping [PDF]
For the investigation of the grain size distribution of the material washed out from the piping, we used 20 samples originating from different places on the Danube and the Tisza rivers.
Nađ Laslo
doaj +1 more source
Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells [PDF]
The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture.
Bongard, Robert D +3 more
core +2 more sources
NAD+ metabolism controls inflammation during senescence
We have recently discovered that nicotinamide adenine dinucleotide metabolism controls the pro-inflammatory senescence-associated secretory phenotype during cellular senescence.
Timothy Nacarelli, Rugang Zhang
doaj +1 more source
“NAD-capQ” detection and quantitation of NAD caps [PDF]
RNA 5′ cap structures comprising the metabolic effector nicotinamide adenine dinucleotide (NAD) have been identified in diverse organisms. Here we report a simple, two-step procedure to detect and quantitate NAD-capped RNA, termed “NAD-capQ.” By use of NAD-capQ we quantitate NAD-capped RNA levels in Escherichia coli, Saccharomyces cerevisiae, and human
Grudzien-Nogalska, Ewa +3 more
openaire +2 more sources
Sirtuin activators as an anti-aging intervention for longevity [PDF]
Sirtuins are a family of NAD+-dependent class III histone deacetylases that regulate histones and other proteins. The mammalian sirtuins comprise seven members that have a role in energy metabolism, DNA repair, inflammation, cell survival, apoptosis ...
Puja Sah, Anita K. Rai, Donkupar Syiem
doaj +1 more source
Characterization of sand boils with grading entropy [PDF]
Grain size and grain distribution by size are dominant factors determining soil behaviour. The shape and position of a grain distribution curve contain implicit information about the propensity of sand boiling or piping at flood conditions. The author
Nađ Laslo
doaj +1 more source
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53 independent pathways [PDF]
Most cancer cells use aerobic glycolysis to fuel their growth. The enzyme lactate dehydrogenase-A (LDH-A) is key to cancer’s glycolytic phenotype, catalysing the regeneration of nicotinamide adenine dinucleotide (NAD þ ) from reduced nicotinamide adenine
Allison, Simon J. +6 more
core +1 more source
Natural pentafuranosylnucleos(t)ides and their analogs: structure, functions, synthesis, and perspective of medical application [PDF]
Pentafuranosylnucleos(t)ides represent a class of natural compounds regulating diverse cell functions being preferably components of biopolymers and also participating as cyclic regulatory low-molecular ligands.
Dmitrii Platov +3 more
doaj +1 more source
Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O +8 more
core +1 more source
Murine iNKT cells are depleted by liver damage via activation of P2RX7
Drug‐induced liver injury activates a suicide pathway in hepatic iNKT cells. The tissue damage induced release of ATP and NAD into the extracellular space triggers the receptor P2RX7 and leads locally to a long‐lasting depletion of iNKT cells. Abstract Invariant natural killer T cells (iNKT) constitute up to 50% of liver lymphocytes and contribute to ...
Astrid A. Bovens +6 more
wiley +1 more source

