Results 91 to 100 of about 19,553 (185)

Serial Llama Immunization with Various SARS-CoV-2 RBD Variants Induces Broad Spectrum Virus-Neutralizing Nanobodies

Vaccines
The emergence of SARS-CoV-2 mutant variants has posed a significant challenge to both the prevention and treatment of COVID-19 with anti-coronaviral neutralizing antibodies. The latest viral variants demonstrate pronounced resistance to the vast majority
Pavel P. Solodkov, Alexander M. Najakshin, Nikolai A. Chikaev, Sergey V. Kulemzin, Ludmila V. Mechetina, Konstantin O. Baranov, Sergey V. Guselnikov, Andrey A. Gorchakov, Tatyana N. Belovezhets, Anton N. Chikaev, Olga Y. Volkova, Alexander G. Markhaev, Yulia V. Kononova, Alexander Y. Alekseev, Marina A. Gulyaeva, Alexander M. Shestopalov, Alexander V. Taranin   +16 more
doaj   +1 more source

Nanobodies raised against monomeric alpha-synuclein inhibit fibril formation and destabilize toxic oligomeric species [PDF]

, 2017
BACKGROUND: The aggregation of the protein ɑ-synuclein (ɑS) underlies a range of increasingly common neurodegenerative disorders including Parkinson’s disease.
Bryant, CE, Buell, AK, Choi, ML, De Genst, E, Dobson, CM, Gandhi, S, Guilliams, T, Hong, L, Horrocks, MH, Hughes, CD, Iljina, M, Klenerman, D, Knowles, TPJ, Lee, J-E, Lee, SF, Ludtmann, MH, Ruggeri, FS, Vendruscolo, M   +17 more
core  

Quadrupole transitions near interface: general theory and application to atom inside a planar cavity

, 2005
Quadrupole radiation of an atom in an arbitrary environment is investigated within classical as well as quantum electrodynamical approaches. Analytical expressions for decay rates are obtained in terms of Green function of Maxwell equations.
A. S. Davydov, D. Bloch, E. M. Lifshitz, E. M. Purcell, G. Dutier, G. Hass, J. A. Stratton, M. Ducloy, V. V. Klimov, V. V. Klimov   +9 more
core   +1 more source

Development of nanobodies against the coat protein of maize chlorotic mottle virus

FEBS Open Bio
Maize lethal necrosis (MLN) is a maize disease caused by the maize chlorotic mottle virus (MCMV), a potyvirus which causes yield losses of 30–100%. The present study aimed to isolate nanobodies against the MCMV coat protein (CP) for the diagnosis of MLN.
Faith Njeru, Olivier Zwaenepoel, Geert Haesaert, Gerald Misinzo, Kris De Jonghe, Jan Gettemans   +5 more
doaj   +1 more source

Nanobodies: From Discovery to AI-Driven Design

Biology
Nanobodies, derived from naturally occurring heavy-chain antibodies in camelids (VHHs) and sharks (VNARs), are unique single-domain antibodies that have garnered significant attention in therapeutic, diagnostic, and biotechnological applications due to ...
Haoran Zhu, Yu Ding
doaj   +1 more source

Implementation of a Novel Nanobody Panel for the Efficient Capture of Extracellular Vesicles from Human Plasma

Molecules
Extracellular vesicles (EVs) are nanoscale particles released by cells and are significant components in intercellular communication. Their ability to reflect the molecular state of parental cells and their presence in body fluids make them increasingly ...
Marija Tursunović, Lidija Filipović, Ninoslav Mitić, Sanja Stevanović, Milica Spasojević Savković, Ario de Marco, Milica Popović   +6 more
doaj   +1 more source

Research Note: Clostridium perfringens NetB and CnaA neutralizing nanobodies in feed reduce the incidence of poultry necrotic enteritis

Poultry Science
: Necrotic enteritis is a devastating disease to poultry caused by the bacterium Clostridium perfringens. As a novel approach to combating poultry necrotic enteritis, we identified and characterized several hundred single domain antibody fragments (or ...
Slade A. Loutet, Sylvia Cheung, Sarah Zaytsoff, Charles Hofacre, Matthew K. Jones, Filip Van Petegem, Hamlet Abnousi   +6 more
doaj   +1 more source

SARS-CoV-2 nanobodies 2.0 [PDF]

Signal Transduction and Targeted Therapy, 2021
Fabien Labroussaa, Joerg Jores
openaire   +4 more sources

Plasmon oscillations in ellipsoid nanoparticles: beyond dipole approximation

, 2008
The plasmon oscillations of a metallic triaxial ellipsoid nanoparticle have been studied within the framework of the quasistatic approximation. A general method has been proposed for finding the analytical expressions describing the potential and ...
A. A. Oraevsky, A. B. Evlyukhin, A. Charalambopoulos, A. F. Stevenson, A. Irimia, C. Sonnichsen, C. Sonnichsen, D. J. Bergman, D. V. Guzatov, D. V. Guzatov, D.-S. Wang, E. T. Whittaker, E. W. Hobson, F. Claro, F. D. Dyson, G. Perrusson, H. F. Hamann, H. Raether, H.X. Xu, I. I. Smolyaninov, J. A. Stratton, J. Gersten, J. Grand, J. R. Lakowicz, K. Kneipp, M. Brongersma, M. L. Levin, M. Rahman, M. Tejedor, M. Yu. Pikhota, N. N. Voitovich, O. E. Lysenko, O. Muskens, P. Mazeron, P. Muhlschlegel, R. Ruppin, R. Ruppin, S. A. Maier, S. Chah, S. Kawata, T. Kalkbrenner, T. Vo-Dinh, V. V. Klimov, V. V. Klimov, V. V. Klimov, V. V. Klimov, V. V. Klimov, W. C. Chew, W. D. Niven, Y. A. Urzhumov, Y. Liu, Z. Liu   +51 more
core   +1 more source

Selection of Functional Intracellular Nanobodies

SLAS Discovery, 2019
Camelid-derived nanobodies are versatile tools for research, diagnostics, and therapeutics. Certain nanobodies can function as intrabodies and bind antigens within the eukaryotic cytosol. This capability is valuable for the development of intracellular probes and targeted gene therapies.
openaire   +2 more sources