Results 141 to 150 of about 16,217 (195)
Functional Suitability Evaluation of Radioimmunoconjugates of Nanobodies against PD-L1 and HER2/neu for Tumor Theranostics. [PDF]
Avrov KO +9 more
europepmc +1 more source
Disease Biomarker Detection Using Fluorescence Polarization Assays: Principles and Clinical Applications. [PDF]
Mukhametova LI, Eremin SA, Tsakalof AK.
europepmc +1 more source
Nanobodies in therapeutic applications.
Over the years, many antibodies have been successfully generated to treat patients with life-threatening diseases, most notably cancer. While the first generation of antibodies, originating from mice, caused severe side effects and were relatively inefficient, technological advances have made it possible to obtain fully human antibodies for therapeutic
Roovers, R.C. +2 more
openaire +3 more sources
Nanobodies as novel agents for disease diagnosis and therapy
Christina G Siontorou Department of Industrial Management and Technology, University of Piraeus, Piraeus, Greece Abstract: The discovery of naturally occurring, heavy-chain only antibodies in Camelidae, and their further development into small ...
Christina G. Siontorou
exaly +1 more source
Radiolabeling Strategies of Nanobodies for Imaging Applications
Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to ...
Ralph A Bundschuh +2 more
exaly +2 more sources
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Annual Review of Animal Biosciences, 2021
Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via one single domain, known as VHH or Nanobody. This serendipitous discovery made three decades ago has stimulated a growing number of researchers to generate highly specific ...
openaire +2 more sources
Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via one single domain, known as VHH or Nanobody. This serendipitous discovery made three decades ago has stimulated a growing number of researchers to generate highly specific ...
openaire +2 more sources

