Results 141 to 150 of about 16,217 (195)

Functional Suitability Evaluation of Radioimmunoconjugates of Nanobodies against PD-L1 and HER2/neu for Tumor Theranostics. [PDF]

open access: yesSovrem Tekhnologii Med
Avrov KO   +9 more
europepmc   +1 more source

Nanobodies in therapeutic applications.

open access: yesCurrent opinion in molecular therapeutics, 2007
Over the years, many antibodies have been successfully generated to treat patients with life-threatening diseases, most notably cancer. While the first generation of antibodies, originating from mice, caused severe side effects and were relatively inefficient, technological advances have made it possible to obtain fully human antibodies for therapeutic
Roovers, R.C.   +2 more
openaire   +3 more sources

Nanobodies as novel agents for disease diagnosis and therapy

open access: yesInternational Journal of Nanomedicine, 2013
Christina G Siontorou Department of Industrial Management and Technology, University of Piraeus, Piraeus, Greece Abstract: The discovery of naturally occurring, heavy-chain only antibodies in Camelidae, and their further development into small ...
Christina G. Siontorou
exaly   +1 more source

Radiolabeling Strategies of Nanobodies for Imaging Applications

open access: yesDiagnostics, 2021
Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to ...
Ralph A Bundschuh   +2 more
exaly   +2 more sources
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Applications of Nanobodies

Annual Review of Animal Biosciences, 2021
Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via one single domain, known as VHH or Nanobody. This serendipitous discovery made three decades ago has stimulated a growing number of researchers to generate highly specific ...
openaire   +2 more sources

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