Results 21 to 30 of about 48,754 (252)
, 2016 1) Distributions of the sampled trajectories using STILT on the Nanog subtree dataset 2) Goodness-of-fit test distributions Related to : Analysis of cell lineage trees by exact Bayesian inference identifies negative autoregulation of Nanog in mouse ...
Feigelman, J (via Mendeley Data)
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Super-Enhancers and CTCF in Early Embryonic Cell Fate Decisions
Frontiers in Cell and Developmental Biology, 2021 Cell fate decisions are the backbone of many developmental and disease processes. In early mammalian development, precise gene expression changes underly the rapid division of a single cell that leads to the embryo and are critically dependent on ...
Puja Agrawal +4 more
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Molecular & Cellular Oncology, 2020 Colorectal cancer (CRC) is one of the most important malignancies and causes of cancer-related deaths worldwide. Cancer stem cell markers identification could be helpful to acquire important prognostic information and develop new treatment regimens. This
Raheleh Roudi +5 more
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Frontiers in Pharmacology, 2016 Proliferation, a key feature of cancer cells, accounts for the majority of cancer-related diseases resulting in mortality. MicroRNAs (miRNAs) plays important post-transcriptional modulation roles by acting on multiple signaling pathways, but the ...
Dan-dan Xu +23 more
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Cells, 2020 NANOG is a transcription factor involved in the regulation of pluripotency and stemness. The functional paralog of NANOG, NANOGP8, differs from NANOG in only three amino acids and exhibits similar reprogramming activity.
Erika Mikulenkova +4 more
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Identification of Nanog as a novel inhibitor of Rad51 [PDF]
Cell Death & Disease, 2022 AbstractTo develop inhibitors targeting DNA damage repair pathways is important to improve the effectiveness of chemo- and radiotherapy for cancer patients. Rad51 mediates homologous recombination (HR) repair of DNA damages. It is widely overexpressed in human cancers and overwhelms chemo- and radiotherapy-generated DNA damages through enhancing HR ...
Ying Xin +12 more
openaire +3 more sources
Condensates containing Nanog and DNA fragments. [PDF]
, 2023 (A–C) Results of a representative trajectory of 200 Nanog molecules and four DNA segments starting from a fully phase-separated configuration. (A) Time courses of 200 Nanog molecules (cyan) and four DNA (red) along the z-axis (long axis) of the slab. (B)
Cheng Tan (293674) +3 more
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Сеченовский вестник, 2023 The development of neurodegenerative diseases is associated with proper neuronal circuit formation, axonal guidance. The DCC receptor (deleted in colorectal cancer / colorectal cancer suppressor) and SHH (sonic hedgehog protein) are among the key ...
D. D. Kotelnikov +3 more
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Functional analysis of the Nanog tryptophan repeat [PDF]
, 2020 The homeodomain transcription factor NANOG promotes self-renewal of embryonic stem cells (ESCs) and specification of primordial germ cells (PGCs). NANOG binds thousands of sites within the ESC genome together with OCT4, SOX2 and RNA polymerase II (RNAPII)
Vojtek, Matúš
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Acta Veterinaria, 2023 Epidermis stem cells have a crucial role through the processes of proliferation and differentiation, to replace cells that are constantly lost during tissue turnover or following injury.
Lužajić Božinovski Tijana +7 more
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