Results 101 to 110 of about 12,068 (208)
Podocytes: recent biomolecular developments
Biomolecular Concepts, 2014 Podocytes are postmitotic renal glomerular cells with multiple ramifications that extend from the cell body. Processes departing from a podocyte interdigitate with corresponding projections from neighboring cells and form an intricate web that enwraps ...
Armelloni Silvia +9 more
doaj +1 more source
Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery
PROTEOMICS, Volume 25, Issue 21-22, Page 102-150, November 2025.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam +12 more
wiley +1 more source
Podocin Regulates the Nephrin-Nephrin Distance in the Glomerular Pore [PDF]
Biophysical Journal, 2020 Gusztav Schay +6 more
openaire +1 more source
Optimizing (Bio) Catalysis with Liquid‐Liquid Phase Separation Systems
ChemSystemsChem, Volume 7, Issue 6, November 2025.This review highlights how LLPS creates membraneless compartments involved in different scenarios in nature. It further explores different examples that focus on the development of synthetic coacervates that enhance catalytic efficiency by concentrating reactants, or by the direct influence of the coacervates building blocks themselves.
David Q. P. Reis +4 more
wiley +1 more source
Detection of podocyturia in patients with lupus nephritis [PDF]
, 2013 INTRODUCTION: The podocyturia has been detected in glomerular diseases, such as lupus nephritis (LN), in which proteinuria is an important manifestation, and its occurrence seems to be limited to the active phase of the disease.
Mansur, Juliana Busato +5 more
core +3 more sources
Development of a Novel Diagnostic Test Using Podocyturia as a Biomarker for Detection of Kidney Damage [PDF]
, 2013 Primary glomerular diseases are the most common cause of progressive chronic kidney disease (CKD) in dogs, a common and significant source of illness that often progresses to kidney failure.
Farooqi, Eesha
core +1 more source
Der Einfluss endogener und exogener Faktoren auf Podozyten und Nierenfunktion [PDF]
, 2018 Einleitung: Humane Podozyten (hPC) stellen hochdifferenzierte Zellen dar, die einen elementaren Bestandteil der renalen Filtrationsbarriere bilden. Ihre intensive Erforschung in vitro ist erst seit wenigen Jahren möglich.
Langer, Sebastian
core +1 more source
Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2:Implications for podocyte depletion and proteinuria in diabetes mellitus [PDF]
, 2015 Advanced glycation end-products (AGEs) are implicated in the pathogenesis of diabetic nephropathy (DN). N-carboxymethyl-lysine (CML) is one of the predominant AGEs that accumulate in all renal compartments of diabetic patients.
Kumar, P Anil +5 more
core +2 more sources
Biological Research, 2007 Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases.
RODRIGO GONZÁLEZ +7 more
doaj
BiomedicinesBackground/Objectives: Nephrotic syndrome, a glomerular disease caused by podocyte dysfunction, is characterized by proteinuria, hypoalbuminemia, edema, and hyperlipidemia.
Astrid K. Kardani +3 more
doaj +1 more source