Results 81 to 90 of about 3,007 (176)
Scientific Reports, 2017 SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1.
Ping Li +5 more
doaj +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source
Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment
Journal of Cellular Physiology, Volume 241, Issue 5, May 2026.ABSTRACT Single‐cell mechanical properties such as stiffness, elasticity, and viscosity, are crucial in governing biological processes like migration, proliferation, and differentiation. In cancer, the mechanical properties of cells undergo significant alterations, which contribute to tumor growth, metastasis, and resistance to therapy.
Merve Sevgi +7 more
wiley +1 more source
, 2014 Products of conventional PCR were separated on agarose gels. The 27 human cDNA samples, as shown in Table 1, were used in A and B. For DV23, the upper band contained the DV23 region and the lower band lacked the DV23 region. Specific primer pairs spanned:
Le Thanh Lam (33460) +6 more
core +1 more source
Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications
Exploration, Volume 6, Issue 2, April 2026.Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu +8 more
wiley +1 more source
, 2012 A) Genomic map of the nesprin-2 gene highlighting the positions of the nesprin-1 UTRs identified to date. B) Proposed nesprin-2 isoforms created by alternative transcription.
Jason A. Mellad (154523) +4 more
core +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.Whole exome sequencing analysis on 55 couples and miscarriages from their current pregnancies reveals a significant heterogeneity and complexity in exomic variants contributing to RPL. ABSTRACT Background This study aimed to identify candidate genes for recurrent pregnancy loss (RPL).
Fanjuan Kong +4 more
wiley +1 more source
Identification of nesprin-1 and nesprin-2 splicing events.
, 2012 A) PCR amplification across splice sites was carried out from cDNA isolated from U2OS cells. Splicing of exon 93 for nesprin-1 was observed as was the splicing for nesprin-2 exon 107’.
Jason A. Mellad (154523) +4 more
core +1 more source
Nuclear Envelope Transmembrane Proteins in Myotonic Dystrophy Type 1
Frontiers in Physiology, 2018 Myotonic dystrophy type 1 (DM1) is a multisystemic disorder with predominant myotonia and muscular dystrophy which is caused by CTG-repeat expansions in the DMPK gene. These repeat expansions are transcribed and the resulting mRNA accumulates RNA-binding
Stefan Hintze +4 more
doaj +1 more source
, 2014 Quantitative PCR to show mRNA expression of nesprin isoforms relative to the expression of two endogenous house-keeping controls. Charts represent the mean relative expression ± SEM, measured in cDNA preparations from 20 human tissues and 7 cell lines ...
Le Thanh Lam (33460) +6 more
core +1 more source