Results 21 to 30 of about 3,321 (184)

Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study [PDF]

open access: yesBMC Medicine, 2020
Background High consumption of red and processed meat is commonly associated with increased cancer risk, particularly colorectal cancer. Antibodies against the red meat-derived carbohydrate N-glycolylneuraminic acid (Neu5Gc) exacerbate cancer in “human ...
Salam Bashir   +18 more
doaj   +2 more sources

Detection of the Dietary xenoglycan N-glycolylneuraminic Acid (Neu5Gc) and anti-Neu5Gc Antibodies within Reproductive Tracts of Male and Female Infertility Subjects [PDF]

open access: yesClinical Obstetrics, Gynecology and Reproductive Medicine, 2015
Objective To assess the frequency of dietary xenoglycanNeu5Gc and antibodies in males and females and its impact on fertility. Design Prospective study of semen, uterine lavage, and follicular fluid from subjects undergoing infertility evaluation or in ...
Ressler, Ilana B.   +9 more
core   +5 more sources

Generation of recombinant anti-N-glycolylneuraminic acid (Neu5Gc) scFv and its applications for detection and quantitation of Neu5Gc

open access: yes, 2016
Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation and in disease processes such
Sharma, Rajesh Kumar
core   +2 more sources

Exposure of Children to Rural Lifestyle Factors Associated With Protection Against Allergies Induces an Anti-Neu5Gc Antibody Response [PDF]

open access: yesFrontiers in Immunology, 2019
Rural lifestyle has been shown to be highly protective against the development of allergies. Contact to farm-animals or pets and early-life consumption of milk products turned out to be important.
Remo Frei   +9 more
doaj   +2 more sources

From “Serum Sickness” to “Xenosialitis”: Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc

open access: yesFrontiers in Immunology, 2019
The description of “serum sickness” more than a century ago in humans transfused with animal sera eventually led to identification of a class of human antibodies directed against glycans terminating in the common mammalian sialic acid N ...
Aniruddha Sasmal   +2 more
exaly   +3 more sources

Chemo-enzymatic synthesis of Neu5Gc-containing sialylated lactulose [PDF]

open access: yesTropical Journal of Pharmaceutical Research, 2017
Purpose: To synthesize novel sialylated lactuloses, namely, Neu5Gc-α2,3-lactulose and Neu5Gc-α2,6-lactulose.Methods: ManNGc was chemically synthesized from commercially available N-acetylmannosaime (ManNAc), which was used as the donor substrate to ...
Li, Bangbang   +6 more
core   +4 more sources

Anti-Neu5Gc Antibody Kit Protocols v1

open access: yes, 2016
Anti-Neu5Gc Antibody Kit Protocols for Flow Cytometry, ELISA, and Western blot.
Kelsey Miller
core   +2 more sources

Anti-Neu5Gc Antibody Kit Protocol - ELISA v2

open access: yes, 2017
This protocol is essentially the same as a standard ELISA protocol, with one major exception – all animal compounds must be avoided in buffers, etc. because they contain Neu5Gc, which will interfere with antibody activity and result in misleading data ...
Kelsey Miller
core   +2 more sources

Species-specific N-glycan patterns in animal and human breast milk samples [PDF]

open access: yesFrontiers in Nutrition
The main components of milk are protein, fat and carbohydrates. Glycans are complex carbohydrate structures covalently bound to proteins and lipids or exist freely in solutions.
Davide Ret   +6 more
doaj   +2 more sources

Anti-Neu5Gc Antibody Kit Protocol - ELISA v1

open access: yes, 2016
This protocol is essentially the same as a standard ELISA protocol, with one major exception – all animal compounds must be avoided in buffers, etc. because they contain Neu5Gc, which will interfere with antibody activity and result in misleading data ...
Kelsey Miller
core   +2 more sources

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