Results 11 to 20 of about 7,614 (192)

Retinal Morphological Characterization of Collared Scops Owl (Otus lettia) Using Optical Coherence Tomography and Histological Techniques. [PDF]

Vet Ophthalmol
ABSTRACT Objective To establish normative retinal imaging and measurement data for the Collared Scops Owl (Otus lettia), a nocturnal raptor clinically free of systemic and ophthalmological disorders, using optical coherence tomography and histopathology.
Chiu YS, Chie CH, Colitz CMH, Huang WH, Yang YW, Lin CT.   +5 more
europepmc   +2 more sources

TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia

CNS Neuroscience &Therapeutics, EarlyView., 2023
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi, Decheng Ren, Fan Yuan, Zhou Zhang, Daizhan Zhou, Xin Yi, Lei Ji, Keyi Li, Fengping Yang, Xi Wu, Xingwang Li, Yifeng Xu, Yun Liu, Peng Wang, Changqun Cai, Chuanxin Liu, Qian Ma, Lin He, Yi Shi, Guang He   +19 more
wiley   +1 more source

Toxicity of Triamcinolone Acetonide on Retinal Neurosensory and Pigment Epithelial Cells

Investigative Opthalmology & Visual Science, 2006
To study the toxicity of triamcinolone acetonide (Kenalog; Bristol-Meyers Squibb, Princeton, NJ) on retinal pigment epithelial (ARPE-19) and retinal neurosensory (R28) cells.ARPE-19 and R28 were grown in tissue culture in Dulbecco's modified Eagle's medium (DMEM) containing 10% fetal bovine serum.
Raja, Narayanan, Jeanie K, Mungcal, M Cristina, Kenney, Gail M, Seigel, Baruch D, Kuppermann   +4 more
openaire   +2 more sources

INVESTIGATION OF NEUROPROTECTIVE ACTIVITY THIOPHANE INVOLUTIONAL CHORIORETINAL DEGENERATION IN RATS OXYS

Бюллетень сибирской медицины, 2013
The method of spontaneous and induced luminol -dependent chemiluminescence in homogenates of rat retinas OXYS registered increase in the generation of free radicals against decrease in total antioxidant  activity.
A. A. Zhdankina, G. A. Kon, M. B. Plotnikov, Ye. Yu. Varakuta, S. V. Logvinov, A. Ye. Prosenko, N. G. Kolosova   +6 more
doaj   +1 more source

Effects of a high-fat, high-carbohydrate diet on the retina of young and old rats

Бюллетень сибирской медицины, 2023
Aim. To study the effect of a high-fat, high-carbohydrate diet on retinal morphology of young and old rats in the experiment.Materials and methods. The study was carried out on male Wistar rats aged 60 and 450 days at the beginning of the experiment. The
S. V. Logvinov, L. R. Mustafina, B. K. Kurbatov, N. V. Naryzhnaya, E. Yu. Varakuta, A. V. Potapov   +5 more
doaj   +1 more source

Positive Rotational Internal Limiting Membrane Covering Technique for Large Idiopathic Macular Holes. [PDF]

J Ophthalmol
Purpose This article aims to determine the efficacy of a modified technique by a positive rotational internal limiting membrane (ILM) covering for the treatment of large idiopathic macular holes (IMHs). Methods A prospective analysis was conducted on a cohort of 13 patients with large IMH (> 400 μm).
Xi H, Song Y, Ni Y, Cao Y, Zhu T, Fan W, Liu H.   +6 more
europepmc   +2 more sources

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto, Greco A., La Cava M, Lambiase A, Limoli PG, Nebbioso M   +5 more
core   +1 more source

NLRP3 and autophagy in retinal ganglion cell inflammation in age-related macular degeneration: potential therapeutic implications [PDF]

International Journal of Ophthalmology
Retinal degenerative diseases were a large group of diseases characterized by the primary death of retinal ganglion cells (RGCs). Recent studies had shown an interaction between autophagy and nucleotide-binding oligomerization domain-like receptor 3 ...
Xiao-Li Wang, Yun-Xia Gao, Qiong-Zhen Yuan, Ming Zhang   +3 more
doaj   +1 more source

Microfluidic and Microscale Assays to Examine Regenerative Strategies in the Neuro Retina

Micromachines, 2020
Bioengineering systems have transformed scientific knowledge of cellular behaviors in the nervous system (NS) and pioneered innovative, regenerative therapies to treat adult neural disorders.
Maribel Vazquez
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources